Table 1 Clinicopathological variables and the expression of TfR1 and VEGF
From: Transferrin receptor-1 and VEGF are prognostic factors for osteosarcoma
TfR1 | P | VEGF | P | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
Low(%) | Mild(%) | High(%) | Low(%) | Mild(%) | High(%) | |||||
Sex | Female | 25 | 3(12.0) | 10(40.0) | 12(48.0) | 0.332 | 5(20.0) | 11(44.0) | 9(36.0) | 0.405 |
Male | 28 | 8(28.6) | 9(32.1) | 11(39.3) | 5(17.8) | 8(28.6) | 15(53.6) | |||
Age | ≥ 20 years | 18 | 4(22.2) | 4(22.2) | 10(55.6) | 0.306 | 3(16.7) | 9(50.0) | 6(33.3) | 0.293 |
< 20 years | 35 | 7(20.0) | 15(42.9) | 13(37.1) | 7(20.0) | 10(28.6) | 18(51.4) | |||
Tumor size | < 5 cm | 27 | 6(22.2) | 10(37.0) | 11(40.8) | 0.919 | 6(22.2) | 10(37.0) | 11(40.7) | 0.741 |
≥ 5 cm | 26 | 5(19.2) | 9(34.6) | 12(46.2) | 4(15.4) | 9(34.6) | 13(50.0) | |||
Histologic grade* | I | 15 | 4(26.7) | 8(53.3) | 3(20.0) | 0.04 | 4(26.7) | 9(60.0) | 2(13.3) | 0.02 |
II | 25 | 5(20.0) | 10(40.0) | 10(40.0) | 5(20.0) | 8(32.0) | 12(48.0) | |||
III | 13 | 2(15.4) | 1(7.7) | 10(76.9) | 1(7.7) | 2(15.4) | 10(76.9) | |||
Distant metastasis* | Yes | 23 | 1(4.2) | 11(47.8) | 11(47.8) | 0.029 | 1(4.4) | 13(56.5) | 9(39.1) | 0.008 |
No | 30 | 10(33.3) | 8(26.7) | 12(40.0) | 9(30.0) | 6(20.0) | 15(50.0) | |||
Enneking staging* | I | 12 | 8 (66.7) | 3 (25.0) | 7(36.9) | < 0.001 | 6(50.0) | 4(33.3) | 2(16.7) | 0.004 |
II | 19 | 2 (10.5) | 10(52.6) | 21(43.8%) | 2(10.5) | 10(52.6) | 7(36.9) | |||
III | 22 | 1 (4.5) | 6 (27.3) | 15 (68.2) | 2(9.1) | 5(22.7) | 15(68.2) | |||