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Table 5 The significance test of different parameters on tophi in gout patients

From: Risk factors for the formation of double-contour sign and tophi in gout

Parameters

Groups

Without double-contour sign

With double-contour sign

P value

Age*

36.980 ± 10.940

42.640 ± 12.112

0.011

BUN (mmol/L)

5.043 ± 1.380

5.383 ± 1.743

0.372

CREA (μmol/L)

77.488 ± 22.947

76.888 ± 14.758

0.331

UA (μmol/L)*

478.167 ± 145.745

488.704 ± 117.178

0.678

TC (mmol/L)

4.828 ± 1.400

4.789 ± 1.296

0.618

TG (mmol/L)

1.991 ± 1.578

2.208 ± 1.515

0.125

FBG (mmol/L)

5.225 ± 0.674

5.303 ± 1.002

0.751

Sex

Female

1

2

1.000

Male

47

67

BMI

Normal

10

8

0.233

Overweight

19

24

Obesity

19

37

Duration

≤ 1 year

16

11

0.059

1–5 years

22

34

≥ 5 years

10

24

Gout attack in 1 year

0–2 times

24

18

0.019

3–6 times

17

30

7–12 times

7

21

Peak blood UA

421–539

11

13

0.591

≥ 540

37

56

UA level

≤ 421

12

4

0.007

421–539

15

20

≥ 540

21

45

Frequency of UA or renal function examination

Regularly checked

14

4

0.002

Occasionally checked

15

29

Check only when gout attacks

18

35

Eating habits

Strict diet

16

15

0.286

Avoid the high purine diet as much as possible, but not strictly controlled

21

31

No control over diet

11

23

Medication during the interval

Insist on taking

14

6

0.010

Without medications

24

46

Occasional medications

8

17

Hypertensive

No

35

53

0.631

Yes

13

16

CHD

No

48

64

0.149

Yes

0

5

Diabetes

No

47

66

0.884

Yes

1

3

CKD

No

45

67

0.677

Yes

3

2

Other diseases

No

29

43

0.835

Yes

19

26

Hyperlipidemia

No

43

66

0.364

Yes

5

3

Kidney stones

Yes

12

13

0.782

No

30

37

Tophi

Yes

10

16

0.140

No

18

13

Ever done a joint US

Done

11

1

< 0.001

Never done

37

66

Whether there is a long-term treatment plan for gout

Yes

21

15

0.011

No

27

54

Understand gout

Understand

14

10

0.050

A little

26

35

Not understand

8

23

Knowledge of high purine food

Fully understand

17

15

0.083

A little

25

33

Unknown

6

19

  1. UA uric acid, CHD coronary heart disease, CKD chronic kidney disease, US ultrasound. P < 0.05 was considered as significantly different
  2. *t test