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Table 2 Association between baseline patient characteristics and mortality according to Cox regression analysis, unadjusted and adjusted for potential confounders

From: The impact of warfarin on operative delay and 1-year mortality in elderly patients with hip fracture: a retrospective observational study

  Unadjusted Cox regression model Adjusted Cox regression model
Crude HR CI 95% p value Adjusted HR CI 95% p value
Age (ref: 65–74 yrs)
 75–84 yrs 1.13 0.69–1.84 0.633 0.88 0.53–1.45 0.621
 85–94 yrs 2.27 1.43–3.61 0.001 1.48 0.92–2.39 0.107
 ≥ 95 yrs 4.33 2.47–7.57 < 0.001 2.96 1.65–5.31 < 0.001
Gender (ref: male)
 Female 0.63 0.50–0.80 < 0.001 0.71 0.55–0.90 0.005
Therapy (ref: control group)
 Warfarin 2.15 1.59–2.92 < 0.001 1.42 1.03–1.95 0.034
 Antiplatelet 1.23 0.96–1.58 0.10 0.95 0.73–1.23 0.687
ASA score (ref: 1/2)
 3 3.27 1.20–8.91 0.021 1.72 0.62–4.79 0.300
 4/5 7.79 2.90–20.96 < 0.001 2.46 0.87–6.92 0.089
CCI 1.32 1.26–1.39 < 0.001 1.24 1.17–1.32 < 0.001
Time to surgery (ref: < 48 h)
 > 48 h 1.24 0.99–1.56 0.066 1.53 1.04–2.25 0.032
Blood loss (ref: 0–490 ml)
 491–980 ml 1.92 1.38–2.66 < 0.001 1.60 1.14–2.23 0.006
 981–1470 ml 1.97 1.36–2.88 < 0.001 1.38 0.94–2.04 0.097
 > 147 ml 2.60 1.88–3.59 < 0.001 1.81 1.30–2.53 < 0.001
AO/OTA Classification (ref: lateral fracture—A)
 Medial fracture—B 0.89 0.71–1.12 0.332    
Types of surgical Procedure (ref: fixation)
 Reconstruction 0.93 0.74–1.17 0.515