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Table 2 Quality assessment by using the Newcastle-Ottawa Scale for the included studies

From: Reference markers of bone turnover for prediction of fracture: a meta-analysis

 

Chapurlat [7]

Garnero [14]

Gerdhem [17]

Meier [19]

Dobnig [20]

Bauer [21]

Shigdel [10]

Dai [6]

Crandall [8]

Cohort study

 Representativeness of the exposed cohort

+

+

+

+

+

+

+

 Selection of the unexposed cohort

+

+

+

+

+

+

+

+

 Ascertainment of exposure

+

+

+

+

+

+

+

+

+

 Outcome of interest not present at the start of the study

Control for important factor or additional factor

 Study controls for age/sex

+

+

+

+

+

+

+

 Study controls for any other confounding factors

+

+

+

+

 Outcome assessment

+

+

+

+

+

+

+

+

+

 Follow-up long enough for outcomes to occur

+

+

+

+

+

+

+

+

 Adequacy of follow-up of cohorts

+

+

+

+

+

+

+

+

+

 Total quality scores

7

4

8

7

6

6

8

8

7