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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Bovine bone particulates containing bone anabolic factors as a potential xenogenic bone graft substitute

Fig. 1

BBMP decreases osteoblast viability and dose-dependently increases osteoblast mineralisation. Effects of increasing concentrations of BBMP on (a) primary rat osteoblast viability, as determined by alamarBlue® assay and (b) von Kossa staining of bone nodules in primary rat osteoblasts cultured for 21 days. Data presented are the means of three biological experiments ± SEM. One-way ANOVA with post hoc Dunnett. *Significantly different from control (P < 0.05). (c–f) Representative images of von Kossa stained osteoblasts following 21-day culture with BBMP

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X