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Table 2 Elution profiles for oritavancin (n = 3) and vancomycin (n = 3) from polymethylmethacrylate (PMMA)

From: Oritavancin polymethylmethacrylate (PMMA)—compressive strength testing and in vitro elution

 

Mean Cmax (μg/ml)

Mean Tmax (h)

Mean AUC0–24 (μg/ml/h)

Mean % elution

Oritavancin

1.7 ± 1.7

2

11.4

1.6%

Vancomycin

21.4 ± 4.0

2

163.9

9.4%

  1. Cmax maximum concentration, Tmax time at which the maximum concentration was reached, AUC0–24 area under the concentration-time curve from 0 to 24 h
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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X