Table 1 SNPs frequencies of gene ER-α in the control and test groups
SNP | SNPs | Control group | Test group | p value | ORa (95% CI) |
|---|---|---|---|---|---|
PvuII c454-397T>C (NCBI ID: rs2234693) | Allele | (Chi-squared) | |||
T | 51.1 (94) | 54.3 (100) | p = 0.60 | 1.13 (0.75–1.71) | |
C | 48.9 (90) | 45.7 (84) | |||
Genotype | |||||
T/T | 21.7 (20) | 23.9 (22) | |||
T/C | 58.7 (54) | 60.9 (56) | p = 0.72 | 1.13 (0.56–2.25) | |
C/C | 19.6 (18) | 15.2 (14) | |||
XbaI c454-351A>G (NCBI ID: rs9340799) | Allele | n = 184 | n = 184 | (Chi-squared) | |
G | 50.5 (93) | 43.0 (79) | p = 0.17 | 1.35 (0.90–2.04) | |
A | 49.5 (91) | 57.0 (105) | |||
Genotype | n = 92 | n = 92 | |||
G/G | 19.5 (18) | 21.7 (20) | p = 0.01 | 1.14 (0.55–2.33) | |
A/G | 62.0 (57) | 42.3 (39) | |||
A/A | 18.5 (17) | 36.0 (33) | |||