Table 2 Subgroup analysis for the need for transfusion
Subgroup | No. trials | RR (95% CI) | P value | I2 (%) | Test of interaction, P |
|---|---|---|---|---|---|
Risk of bias | |||||
Low | 4 | 0.60 (0.38, 0.95) | 0.028 | 35.5 | 0.047 |
Unclear/high | 3 | 0.50 (0.21, 1.16) | 0.105 | 0 | |
Dose of TXA | |||||
Low | 4 | 0.60 (0.38, 0.93) | 0.014 | 34.1 | 0.125 |
High | 3 | 0.50 (0.16, 0.84) | 0.023 | 0 | |
Transfusion protocol | |||||
Strict | 3 | 0.43 (0.18, 1.05) | 0.064 | 0 | 0.043 |
Loose | 4 | 0.63 (0.40, 0.98) | 0.041 | 14.5 | |