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Table 3 Univariate and multivariable odds ratio of risk factors for the prediction of re-nonunion

From: Factors associated with development of re-nonunion after primary revision in femoral shaft nonunion subsequent to failed intramedullary nailing

Variable N Comparison Univariate analyses Multivariate analyses
OR p value OR p value
Estimate 95% CI Estimate 95% CI
Sex 63 Female vs. male 3.197 0.92, 11.07 0.067 2.801 0.68, 11.49 0.153
Age (years) 63 < 25 vs.25~ 45 vs.> 45 0.816 0.24, 1.41 0.825 0.636 0.30, 2.17 0.589
Smoking 63 Yes vs. no 0.214 0.02, 1.34 0.036* 0.372 0.09, 1.70 0.419
Alcohol abuse 63 Yes vs. no 0.762 0.21, 1.55 0.366 0.791 0.18, 2.02 0.602
BMI (kg/m2) 63 < 30 vs.≥ 30 0.253 0.10, 1.49 0.021* 0.376 0.17, 1.74 0.314
Cause of injury 63 Traffic injury vs. falling vs. crushing 2.031 0.86, 4.37 0.102 2.310 0.86, 5.12 0.099
Fracture type 63 Closed vs. open 1.179 0.54, 2.49 0.692 0.820 0.36, 1.89 0.618
Type of IMN 63 Antegrade vs. retrograde 2.6974 0.96, 9.81 0.148 2.315 0.67, 8.19 0.178
Use of IMN locking screws 63 Dynamic vs. static 0.608 0.26, 1.38 0.237 0.826 0.34, 2.18 0.682
Site of nonunion 63 Isthmal vs. non-isthmal 0.310 0.07, 1.52 0.011* 0.403 0.11, 1.81 0.277
Primary nonunion time (years) 63 < 1.5 vs.≥ 1.5 0.918 0.28, 3.20 0.914 0.719 0.23, 2.71 0.616
Pathological type of nonunion 63 Atrophic vs. hypertrophic 0.517 0.28, 1.19 0.146 1.629 0.28, 3.26 0.701
Bone defect (mm) 63 < 5 vs. ≥ 5 0.472 0.12, 2.58 0.023* 0.528 0.18, 2.62 0.302
Primary revision method 63 ERN vs. ACP 2.125 0.09, 1.16 0.003* 1.027 0.03, 1.54 0.002*
Adjuvant ABG procedure 63 Yes vs. no 1.912 0.06, 1.08 0.027* 1.024 0.01, 1.36 0.003*
  1. N total number of nonunions, BMI body mass index, IMN intramedullary nailing, ERN exchanging reamed nailing, ACP augmentative compression plating, ABG autogenous bone grafting, CI confidence interval, OR odds ratio
  2. *P<0.05