Table 3 Summary of the results
MIV | MIV + collagenase | MIV + collagenase + GF | MACI | Control | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Subject No | 1 | 2 | 3 | AVG10 | 5 | 6 | 7 | 8 | AVG | 9 | 11 | 12 | AVG | 14 | 15 | 16 | AVG | 17 | 18 | 19 | AVG |
Macroscopic score | 8 | 7 | 4 | 6 | 6 | 5 | 5 | 5 | 5 | 3 | 5 | 3 | 4 | 7 | 5 | 4 | 5 | 3 | 3 | 3 | 3 |
Histologic score: lesion1 | 10 | 8 | 8 | 9 | 6 | 8 | 7 | 7 | 7 | 8 | 8 | 7 | 8 | 10 | 9 | 8 | 9 | 2 | 2 | 2 | 2 |
Histologic score: intact2 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 |
Histologic score: patella3 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 | 24 |
GAG lesion4 | 11.5 | 11.7 | 11.3 | 11.50 | 11.0 | 12.2 | 11.6 | 10.9 | 11.43 | 10.8 | 9.9 | 7.6 | 9.43 | 11.8 | 12.1 | 11.9 | 11.93 | 10.4 | 10.5 | 10.4 | 10.43 |
GAG intact5 | 9.9 | 10.7 | 10.1 | 10.23 | 9.5 | 10.0 | 12.6 | 10.9 | 10.75 | 9.8 | 11.3 | 9.7 | 10.27 | 10.2 | 10.3 | 9.9 | 10.13 | 11.7 | 11.4 | 11.8 | 11.63 |
GAG patella6 | 11.0 | 10.9 | 10.8 | 10.90 | 11.5 | 11.9 | 10.8 | 11.0 | 11.30 | 11.8 | 10.6 | 11.9 | 11.43 | 11.6 | 11.0 | 11.8 | 11.47 | 11.5 | 11.4 | 11.4 | 11.43 |
Collagen type II: lesion7 | 22.5 | 34.7 | 20.6 | 25.93 | 9.2 | 10.0 | 8.6 | 8.0 | 8.95 | 7.5 | 6.7 | 6.4 | 6.87 | 41.8 | 40.0 | 41.5 | 41.10 | 2.5 | 2.4 | 2.5 | 2.47 |
Collagen type II: intact8 | 9.0 | 9.3 | 7.3 | 8.53 | 12.6 | 6.7 | 6.7 | 8.9 | 8.73 | 11.3 | 6.3 | 8.8 | 8.80 | 6.7 | 6.2 | 9.4 | 7.43 | 8.3 | 8.5 | 8.0 | 8.27 |
Collagen type II: patella9 | 8.4 | 7.9 | 7.8 | 8.03 | 8.9 | 9.2 | 7.7 | 8.6 | 8.6 | 7.9 | 8.6 | 9.1 | 8.53 | 8. | 7.8 | 8.2 | 8.30 | 8.5 | 8.6 | 8.8 | 8.63 |