Skip to main content

Table 2 Modified O’Driscoll Scoring System [36, 37]

From: In vivo cartilage tissue engineering

Category Score
1. Nature of predominant tissue
 Cellular morphology
  Hyaline articular cartilage 4
  Partially differentiated mesenchyme 2
  Fibrous tissue or bone 0
2. Structural properties
 Surface integrity
  Smooth and in tact 3
  Superficial horizontal lamination 2
  Fissures: 25–100% of thickness 1
  Significant disruption, including fibrillation 0
 Structural integrity
  Normal 2
  Slight disruption, including cysts 1
  Significant disruption 0
 Thickness
  100% of normal surrounding cartilage 2
  50–100% of normal cartilage 1
  0–50% of normal cartilage 0
 Bonding at adjacent cartilage
  Bonded at both ends 2
  Bonded at one end or partially at both 1
  Not bonded 0
3. Independence from cellular changes of degeneration
 Hypocellularity
  Normal cellularity 3
  Mild hypocellularity 2
  Moderate hypocellularity 1
  Severe hypocellularity 0
 Chondrocyte grouping
  No grouping 2
  Less than 25% of cells 1
  25–100% of cells 0
4. Independence from degenerative changes of adjacent cartilage
 Cellular properties
  Normal cellularity, no grouping 3
  Normal cellularity, mild grouping 2
  Mild or moderate hypocellularity 1
  Severe hypocellularity 0
 Fibrillation
  No fibrillation 3
  Less than 25% of the thickness of cartilage 2
  25–50% of the thickness of cartilage 1
  More than 50% of the thickness of cartilage 0