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Table 1 Summary of reported patients with SAPHO syndrome undergoing PET/CT

From: F-18 FDG PET/CT in 26 patients with SAPHO syndrome: a new vision of clinical and bone scintigraphy correlation

Author/year

Age

Sex

Skin lesions

Sites of osteoarticular symptoms

PET/CT

Bone scintigraphy

ESR (mm/h)

CRP (mg/dL)

Time from onset

Sites of increased tracer uptake

SUVmax

Site of lesions on CT

Characteristics of lesions on CT

Kohlfuerst et al. 2003 [10]

45

M

PPP

Shoulder, tibia(R)

< 36

Tibia, ankle*

NA

ACW

Hyperostosis

ACW, tibia

NA

NA

Pichler et al. 2003 [11]

48

M

PPP, acne, seborrhiasis

ACW

> 48

ACW

NA

ACW

Sclerosis

ACW

NA

NA

Shibakuki et al. 2006 [12]

57

M

PPP, acne

ACW

~ 240

Normal

NA

CS

Bone defect, consolidation

ACW, CS, rib 6,7

15

Normal

Inoue et al. 2007 [13]

74

F

PPP

Back

300

CS, TS

NA

CS, TS, LS

Sclerosis, syndesmophyte, osteophyte formation

CS, TS, LS, SI

Elevated

Elevated

Takeuchi et al. 2007 [14]

50

F

None

Neck, back, lumbus

168

ACW, CS, LS, SI, wrist

1.6

CS, LS, femoral neck

Osteosclerosis, osteolysis

ACW, CS, LS, SI, femoral neck

87

2.5

Patel et al. 2009 [15]

20

F

PPP

Back

N/A

ACW, TS, SI

NA

NA

NA

SC, TS, SI

NA

NA

Abuhid et al. 2010 [16]

44

F

PPP

ACW, SI

36

ACW, SI

2.18

ACW, SI

Sclerosis, irregularities

ACW, SI

NA

NA

Canbaz et al. 2010 [17]

18

F

None

Diffuse, prominent in back

9

TS, LS, pelvis

NA

NA

NA

Spine, pelvic bones

74

NA

Nakamura et al. 2010 [18]

60

F

None

Ankle(Bi), back

N/A

CS, LS, SI(L), shoulder(L)

6.1

NA

NA

NA

99

6.379

Namkoong et al. 2015 [19]

62

M

None

ACW(R)

3

ACW

4.0

None

Normal

NA

NA

13.45

Ikeda et al. 2015 [20]

60

F

Acne

ACW, hands(Bi)

N/A

ACW

NA

ACW

Hyperostosis

NA

NA

NA

Dong et al. 2016 [21]

60

F

PPP

Back

2

TS, SS

NA

TS, SS

Osteolysis

TS, S1

NA

NA

Dong et al. 2016 [21]

51

F

None

Back

7

ACW, LS, SI

NA

ACW, SI

Osteosclerosis

ACW, spine, SI

NA

NA

  1. ACW includes the costochondral, sternoclavicular, manubriosternal, and costosternal articulation, sternum, clavicles, and anterior ribs
  2. ACW anterior chest wall, SI sacroiliac, CS cervical spine, TS thoracic spine, LS lumbar spine, NA not applicable
  3. *With absent uptake in the left SC region