Skip to main content

Table 1 The general characteristic of the included studies

From: Efficacy of naproxen prophylaxis for the prevention of heterotopic ossification after hip surgery: a meta-analysis

Author

Country

Sample (I/C)

Age (I/C)

Surgery

Intervention

Control

Outcomes

Follow-up (weeks)

Study

Beckmann 2015

USA

54/54

35.1/35.1

Hip arthroscopy

Naproxen (500Ā mg, twice daily, total 3Ā weeks

Placebo

1,2,3,4,5

3

RCTs

Vielpeau 1999

France

28/28

66/62.8

THA

Naproxen (250Ā mg, 3 times daily, total 6Ā weeks)

Placebo

1,2,3,5

6

RCTs

Gebuhr 1991

Denmark

28/27

75/70

THA

Naproxen (500Ā mg twice on operation day, 250Ā mg, 3 times daily, total 4Ā weeks)

Placebo

2,3,5

4

RCTs

Gebuhr 1995

Denmark

27/23

72/73

THA

Naproxen (500Ā mg twice daily for 7Ā days from operation day on)

Placebo

1,2,3,4

12

RCTs

  1. 1: the occurrence of HO at 1.5Ā months after surgery; 2: the occurrence of HO at 3Ā months after surgery; 3: the occurrence of HO at 6Ā months after surgery; 4: the occurrence of HO at 12Ā months after surgery; 5: the occurrence of complications
  2. I intervention group, C control group, THA total hip arthroplasty