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Table 2 Comparison of postoperative clinical outcomes between the TXA group and NS group

From: Tranexamic acid reduces hidden blood loss in the treatment of intertrochanteric fractures with PFNA: a single-center randomized controlled trial

Variables TXA study group (n = 37) NS study group (n = 40) P value
Surgical blood loss (mL) 128.85 ± 123.18 98.30 ± 59.10 0.31
Postoperative day 2 drainage. (mL) 89.50 ± 44.77 89.73 ± 33.30 0.98*
Hemoglobin preop. (g/L) 109.50 ± 15.07 112.15 ± 13.31 0.51*
Hemoglobin postop. day 1 (g/L) 102.70 ± 13.18 115.27 ± 60.93 0.37*
Hemoglobin postop. day 3 (g/L) 101.05 ± 11.91 100.30 ± 12.54 0.83*
Hematocrit preop. (%) 32.63 ± 4.28 33.79 ± 3.83 0.31*
Hematocrit postop. day 1 (%) 30.53 ± 3.81 31.15 ± 3.80 0.56*
Hematocrit postop. day 3(%) 30.23 ± 3.23 29.34 ± 5.87 0.54
Estimated visible RBC loss day 3 (mL) 69.26 ± 44.77 58.55 ± 22.10 0.33*
Transfusion rate (%) 11/39 (28.20%) 23/41 (56.09%) 0.01
Transfusion units (U) 24 56  
Estimated total RBC loss day 3 (mL) 279.35 ± 209.11 417.89 ± 289.56 0.049*
Estimated hidden RBC loss day 3 (mL) 210.09 ± 202.14 359.35 ± 290.12 0.049*
  1. *Two-sided Student’s t test; †chi-squared test; TXA tranexamic acid, NS normal-saline