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Table 2 Summary of significantly different outcomes between groups

From: Perioperative systemic steroid for rapid recovery in total knee and hip arthroplasty: a systematic review and meta-analysis of randomized trials

First author (Year) Surgery Outcome assessments Summary of significantly different outcomes between groups
Koh et al. (2013) [12] TKA C, P, PONV Less PONV and pain in DA group, and no significant difference in complications
Fujii et al. (2005) [13] TKA C, PONV 8 mg and 16 mg DA causes Less PONV, but 4 mg DA doesn’t work
Jules-Elysee et al. (2011) [14] TKA C, F, I, L, P, PONV Lower IL-6 level within 12 hrs after surgery, better ROM at discharge, but a higher serum glucose level on arrival to the PACU in HC group, no difference in pain relief, PONV, LOS and complications
McLawhorn et al. (2014) [15] TKA C, L, T Lower levels of PAP and PF1.2 while a higher serum glucose level within the first day after surgery in HC group, no significant difference in complications and LOS
Jules-Elysee et al. (2012) [16] TKA C, F, I, L, P, PONV Less pain and lower IL-6 level within 24 hrs after surgery, better ROM at discharge, but a higher serum glucose level within the first day after surgery in HC group, no difference in PONV, LOS and complications
Bergeron et al. (2009) [17] THA C, F, P Similar results in pain, HHS scores and complications between groups at 6 weeks and 1 year postoperatively
Lunn et al. (2011) [20] TKA C, I, L, P, PONV MP causes better outcomes in pain, CRP levels and PONV events, but no difference in complications and LOS
Backes et al. (2013) [21] TKA/
THA
C, F, L, P, PONV Significant pain relief, faster functional recovery, less PONV and earlier discharge in DA groups
Sculco et al. (2015) [22] THA C, I, L, P, T, Less severe pain and lower IL-6 level while a higher serum glucose level in steroid group, no difference in the levels of PAP and PF1.2, LOS and complications
Lunn et al. (2013) [23] THA C, I, L, P, PONV MP causes better outcomes in pain, CRP levels and PONV events, but no difference in complications and LOS
Kardash et al. (2007) [24] THA C,I,P, PONV Less pain, PONV and lower CRP level in DA group, no difference in complications
  1. C: Complications and adverse events; F: Functions; I: Inflammatory factor
  2. L: LOS, Length of stay; T: Thrombogenic markers; P: Pain
  3. PONV: Postoperative nausea and vomiting
  4. DA: dexamethasone; HC: Hydrocortisone; PD:prednisone; MP methylprednisolone
  5. PAP: plasmin-alpha-2-antiplasmin complex, a kind of thrombogenic markers
  6. PF1.2prothrombin fragment1.2, a kind of thrombogenic markers
  7. CRP: C-reactive protein; IL-6: Interleukin-6
  8. HHS: Harris hip score; ROM: Range of motion