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Table 1 Trials characteristics

From: Comparison of local infiltration analgesia and sciatic nerve block for pain control after total knee arthroplasty: a systematic review and meta-analysis

Studies

Reference type

Cases

Mean age

Female patient

Anesthesia

Drug dose of FNB

Drug dose of SNB

Drug dose of LIA

Concomitant Pain

Follow-up

(SNB/LIA)

(SNB/LIA)

(SNB/LIA)

Tanikawa 2014 [11]

RCT

23/23

72/71

19/20

General anesthesia

20 ml of 0.375% ropivacaine

20 ml of 0.375% ropivacaine

200 mg of ropivacaine and 0.5 ml of adrenaline

IV ketorolac 30 mg, ketoprofen 100 mg, or diclofenac 75 mg

3 months

Gi 2014 [13]

RCT

24/25

78/77

21/24

General anesthesia

20 ml 0.375% ropivacaine

20 ml 0.375% ropivacaine

60 ml 0.5% ropivacaine with 0.3 mg epinephrine

400 mg celecoxib, 20 mg oxycontin, and a 6 mg scopolamine patch topically

1 month

Safa 2014 [12]

RCT

33/32

61/61

18/15

Spinal anesthesia

20 mL of 0.5% ropivacaine

20 mL of 0.5% ropivacaine

50 mL of 0.2% ropivacaine

Celecoxib 200 mg, gabapentin 200 mg and acetaminophen 1 g

1.5–3 months

Nagafuchi 2015 [14]

RCT

17/16

72/73

15/13

General anesthesia

20 mL of 0.375% ropivacaine

20 ml of 0.375% ropivacaine

100 mL of 0.2% ropivacaine

Celecoxib 200 mg, gabapentin 200 mg and acetaminophen 1 g

1 months

Cip 2016 [15]

Non-RCT

16/18

73.4/71.8

12/11

Spinal or general anesthesia

0.2% ropivacaine (4 ml/h)

20 ml ropivacaine 0.2%

0.33% ropivacaine (5 mL/h)

Celecoxib and Oxycodone

NS

Aikawa 2016 [16]

Non-RCT

23/23

72/71

19/20

general anesthesia

20 ml 0.375% ropivacaine

20 ml 0.375% ropivacaine

20 mL of 0.375% levobupivacaine

NS

6 months

  1. SNB sciatic nerve block, LIA local infiltration of analgesia, IV intravenous, NS not stated