| |
Total no. of patients
|
PTE no. (%)
|
PTE
|
DVT no. (%)
|
DVT
|
|---|
|
Risk factors†
|
Univariate model
|
Multivariate model
|
Univariate model
|
Multivariate model
|
|---|
| |
Odds ratio (95% CI)
|
Odds ratio (95% CI)
|
Odds ratio (95% CI)
|
Odds ratio (95% CI)
|
|---|
|
Type of surgery
| | | | | | | |
|
HFS
|
20,986
|
29 (0.1)
|
1
|
–
|
93 (0.4)
|
1
|
1
|
|
TKA
|
5023
|
8 (0.2)
|
1.1 (0.5–2.5)
|
–
|
65 (1.3)
|
2.9 (2.1–4.0)***
|
2.7 (1.9–2.7)***
|
|
THA
|
3856
|
6 (0.2)
|
1.1 (0.5–2.7)
|
–
|
33 (0.9)
|
1.9 (1.3–2.9)**
|
2.1 (1.4–3.2)***
|
|
Sex
| | | | | | | |
|
Male
|
6378
|
3 (0.0)
|
1
|
1
|
22 (0.3)
|
1
|
1
|
|
Female
|
23,487
|
40 (0.2)
|
3.6 (1.1–11.7)*
|
3.5 (1.1–11.3)*
|
169 (0.7)
|
2.1 (1.3–3.3)**
|
1.9 (1.2–2.9)**
|
|
History of VTE
| | | | | | | |
|
No
|
29,816
|
42 (0.1)
|
1
|
1
|
187 (0.6)
|
1
|
1
|
|
Yes
|
49
|
1 (2.0)
|
14.8 (2.0–109.5)**
|
9.8 (1.2–77.5)*
|
4 (8.2)
|
14.1 (5.0–39.6)***
|
11.4 (4.0–32.3)***
|
|
Thrombophilia
| | | | | | | |
|
No
|
29,582
|
41 (0.1)
|
1
|
1
|
184 (0.6)
|
1
|
1
|
|
Yes
|
283
|
2 (0.7)
|
5.1 (1.2–21.3)*
|
4.7 (1.1–19.8)*
|
7 (2.5)
|
4.1 (1.9–8.7)***
|
3.0 (1.4–6.4)**
|
|
Elderly (age)
| | | | | | | |
|
<65
|
3941
|
5 (0.1)
|
1
|
–
|
14 (0.4)
|
1
|
1
|
|
65 to 75
|
5458
|
9 (0.2)
|
1.3 (0.4–3.9)
|
–
|
54 (1.0)
|
2.8 (1.6–5.1)***
|
2.5 (1.4–4.5)**
|
|
>75 year
|
20,466
|
29 (0.1)
|
1.1 (0.4–2.9)
|
–
|
123 (0.6)
|
1.7 (1.0–3.0)
|
2.1 (1.1–3.7)*
|
|
Antipsychotic drug
| | | | | | | |
|
No
|
26,958
|
42 (0.2)
|
1
|
–
|
182 (0.7)
|
1
|
–
|
|
Yes
|
2907
|
1 (0.0)
|
0.2 (0.0–1.6)
|
–
|
9 (0.3)
|
0.5 (0.2–0.9)*
|
–
|
|
Obesity (body mass index )
| | | | | | | |
|
<18.5
|
4971
|
4 (0.1)
|
1
|
–
|
20 (0.4)
|
1
|
–
|
|
18.5 to 25
|
14,331
|
20 (0.1)
|
1.7 (0.6–5.1)
|
–
|
87 (0.6)
|
1.5 (0.9–2.5)
|
–
|
| ≧25 |
5369
|
13 (0.2)
|
3.0 (1.0–9.3)
|
–
|
54 (1.0)
|
2.5 (1.5–4.2)***
|
–
|
|
Unknown
|
5194
|
6 (0.1)
|
1.4 (0.4–5.1)
|
–
|
30 (0.6)
|
1.4 (0.8–2.5)
|
–
|
|
Varicose veins of lower extremity
| | | | | | | |
|
No
|
29,767
|
41 (0.1)
|
1
|
1
|
189 (0.6)
|
1
|
–
|
|
Yes
|
98
|
2 (2.0)
|
15.1 (3.6–63.3)***
|
10.9 (2.5–47.5)**
|
2 (2.0)
|
3.3 (0.8–13.3)
|
–
|
- Abbreviations are the same as Tables 1 and 4.
- *p < 0.05; **p < 0.01; ***p < 0.001
-
†Risk factors with statistical significance are shown. The following factors without statistical significance are not listed: lower limbs paralysis, lower limbs casting, congestive heart failure, respiratory failure, malignant disease, central venous catheter, cancer chemotherapy, pregnancy, severe infections, and estrogen replacement therapy
