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Table 3 Radiographic OA grading

From: The temporal effect of platelet-rich plasma on pain and physical function in the treatment of knee osteoarthritis: systematic review and meta-analysis of randomized controlled trials

Studies Intervention Kellgren Lawrence Ahlbäck
0 I II III IV I II III
Cerza et al.[9] PRP   21 24 15     
  HA   25 22 13     
Duymus et al.[29] PRP    22 11     
  HA    24 10     
  Ozone    23 12     
Filardo et al.[17] PRP 0–IV, Mean ± SD: 2.0 ± 1.1    
  HA 0–IV, Mean ± SD: 2.0 ± 1.1    
Forogh et al.[30]a PRP    7 17     
  CS    8 16     
Görmeli et al.[31] PRP   I–III, 26 13    
  PRP/S
HA 		  I–III, 30
I–III, 25 		14
14 		   
  Placebo   I–III, 27 13    
Li et al.[10] PRP   6 2 4 3    
  HA   6 3 3 3    
Montañez-Heredia et al.[35] PRP   5 10 12     
HA   2 9 15     
Patel et al.[11] a PRP1
PRP2 		      37
36 		11
10 		2
2
  Placebo       25 18 3
Paterson et al.[32] PRP    II–III, 12     
  HA    II–III, 11     
Raeissadat et al.[33] PRP   5 34 29 9    
  HA   0 29 23 10    
Sánchez et al.[13] PRP       45 32 12
  HA       42 32 11
Smith et al.[34] PRP    8 7     
  Placebo    10 5     
Spaková et al.[14] PRP   2 39 19     
  HA   2 37 21     
Vaquerizo et al.[15] PRP    14 26 8    
  HA    18 21 9    
  1. SD standard deviation, PRP/S single-PRP injection followed by saline injections, PRP1 single-PRP injection, PRP2 twice PRP injections
  2. aThe number of knees rather than patients was reported
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