Investigation of MMP-1 genetic polymorphisms and protein expression and their effects on the risk of Kashin-Beck disease in the northwest Chinese Han population

Table 1 The loci information of the six SNPs in MMP-1

SNPs	Alleles^a	SNP location	Minor allele frequency (%)			HWE test (P)
SNPs	Alleles^a	SNP location	KBD	Controls	P values	HWE test (P)
rs2071231	T/G	Intron	21.5	17.5	0.14	0.99
rs7125062	T/C	Intron	15.1	15.7	0.78	0.97
rs470221	G/A	Intron	33.2	29.8	0.45	0.29
rs470558	G/A	Exon	18.1	16.3	0.47	0.36
rs470206	C/T	5′UTR	21.4	20.4	0.86	0.85
rs1144396	C/A	5′UTR	34.1	31.0	0.37	0.46

ISSN: 1749-799X