Fig. 2

The effect of RAPA on collagen density in epidural adhesion issues in the laminectomy sites in groups treated with 0.2 mg/ml RAPA (a), 0.1 mg/ml RAPA (b), 0.05 mg/ml RAPA (c) or the control group (d). Collagen tissue is shown in blue because the sections are stained with Masson’s trichrome. The density of collagen in the sections from the 0.2 mg/ml RAPA-treated group (a) was clearly lower than that in tissue samples from the 0.1 mg/ml RAPA (b) and 0.05 mg/ml RAPA (c) groups and the control group (d). “S” represents the spinal cord. “*” represents the scar adhesion area of epidural. The sections were stained with masson. The magnification was ×100