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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: Local application of rapamycin reduces epidural fibrosis after laminectomy via inhibiting fibroblast proliferation and prompting apoptosis

Fig. 1

Photomicrographs of the epidural adhesions at the laminectomy sites from groups treated with 0.2 mg/ml RAPA (a), 0.1 mg/ml RAPA (b), 0.05 mg/ml RAPA (c) and the control group (d). Loose scar tissues (asterisk) with little adherence to the dura mater (arrow) were found in the 0.2 mg/ml RAPA group (a). Moderate scar tissues (asterisk) were found in the 0.1 mg/ml RAPA group (b). However, dense scar tissues (asterisks) adhered to the dura mater (arrow) were found in the 0.05 mg/ml RAPA (c) group and the control group (d). “S” represents the spinal cord. The sections were stained with haematoxylin–eosin. The magnification was ×200

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X