Table 3 Changes in revascularization, inflammation, fiber structure, and hyaline degeneration scores and number of fibroblasts throughout the experiment for each study group
Week 1 | Week 2 | Week 3 | Week 4 | p a | |
|---|---|---|---|---|---|
Revascularization score | |||||
Erythropoietin group | 3 (3–3) | 1 (1–1) | 0 (0–0) | 0 (0–0) | 0.012 |
Control group | 2 (1–2.5) | 0.5 (0–0.5) | 0 (0–0) | 0 (0–0) | 0.035b |
P for intergroup difference | 0.100 | 0.100 | 1.000 | 1.000 | |
Inflammation score | |||||
Erythropoietin group | 2 (2–3) | 1 (0–1) | 1 (0–1) | 0 (0–1) | 0.061 |
Control group | 3 (2–3) | 1 (0–1) | 0 (0–1) | 0.5 (0–1) | 0.075 |
P for intergroup difference | 0.700 | 1.000 | 0.700 | 0.800 | |
Fiber structure score | |||||
Erythropoietin group | 1 (0–1) | 1 (1–1) | 2 (2–2) | 3 (3–3) | 0.015 |
Control group | 1 (1–1) | 2 (2–2) | 3 (3–3) | 3 (3–3) | 0.019 |
P for intergroup difference | 0.700 | 0.100 | 0.100 | 1.000 | |
Hyaline degeneration score | |||||
Erythropoietin group | 0 (0–0) | 1 (0–1) | 1 (1–3) | 2 (1–3) | 0.051 |
Control group | 0 (0–0) | 1 (1–2) | 3 (1–3) | 2.5 (2–3) | 0.053 |
P for intergroup difference | 1.000 | 0.400 | 0.700 | 0.800 | |
Number of fibroblasts | |||||
Erythropoietin group | 22 (8–28) | 40 (32–47) | 54 (40–54) | 27 (12–30) | 0.030b |
Control group | 20 (16–33) | 45 (27–52) | 44 (30–45) | 32 (30–35) | 0.272 |
P for intergroup difference | 1.000 | 1.000 | 0.400 | 0.200 |