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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: Reduction of intraarticular adhesion of knee by local application of rapamycin in rabbits via inhibition of fibroblast proliferation and collagen synthesis

Fig. 3

The collagen density of intraarticular adhesion tissue in the RAPA groups (0.2mg/ml (a), 0.1mg/ml (b), 0.05mg/ml (c) and the control group (d). The collagen tissues show blue in the section with Masson’s trichrome staining under the light microscope (×200). RAPA could reduce collagen synthesis and fibrosis. The density of collagen tissue in the 0.2 mg/ml RAPA group and the 0.1 mg/ml RAPA group revealed a significant decrease compared with those in the 0.05 mg/ml RAPA group and control group

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X