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Table 2 Histological grading of healed rotator cuffs, as scored by a specialist musculoskeletal pathologist and an orthopaedic registrar based on the criteria set out in Table 1

From: Augmentation with an ovine forestomach matrix scaffold improves histological outcomes of rotator cuff repair in a rat model

Group Collagen fibre density Collagen fibre orientation Bone-tendon interface Vascularity Inflammation Total
6 weeks       
 Sham 2.5 (±0.29) 2.5 (±0.29) 2.5 (±0.29) 2.5 (±0.29) 2.5 (±0.29) 11 (±0.91)
 Unaugmented 1.5 (±0.5) 0.75* (±0.48) 1 (±0.71) 1* (±0.41) 1* (±0) 5.25* (±1.60)
 OFM augmentation 1.25 (±0.25) 1.25 (±0.25) 1 (±0.65) 0.25* (±0.25) 1* (±0) 5.25* (±0.85)
12 weeks       
 Sham 2.75 (±0.25) 2.75 (±0.25) 2 (±0.71) 1.25 (±0.48) 2 (±0) 10.75 (±1.44)
 Unaugmented 1.5 (±0.5) 0.5* (±0.29) 0.5 (±0.5) 0.5 (±0.29) 1.25 (±0.25) 4.25* (±1.60)
 OFM augmentation 2 (±0) 1.25* (±0.25) 2 (±0.41) 0.25 (±0.25) 1.5 (±0.29) 7 (±1)
  1. Data presented are the mean of both scorers ±SEM. One-way ANOVA with post hoc Tukey’s test. N = 2
  2. *p < 0.05 compared to sham