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Table 3 Blood loss, length of hospital stay and complications after total knee arthroplasty

From: Bridging therapy for oral anticoagulation increases the risk for bleeding-related complications in total joint arthroplasty

  UFH bridging LMWH bridging LMWH prophylaxis p value
(n = 4) (n = 8) (n = 1000)
Blood loss     
 Preop. haemoglobin level, mmol/L (range) 8.5 (8.0–9.2) 8.6 (7.6–10.3) 8.5 (6.2–10.9)a 0.902
 Postop. haemoglobin level, mmol/L (range) 5.6 (4.9–6.0) 6.4 (5.0–9.0) 6.5 (4.0–9.9)b 0.104
 Haemoglobin decrease, mmol/L (range) 3.0 (2.1–3.9) 2.2 (1.3–4.2) 2.0 (0.2–4.8)c 0.012
 Transfusion units n (range) 0.5 (0–2) 0 (0) 0.15 (0–9) 0.449
  Median 0.0 0.0 0.0  
 Bleeding index Mean (range) 3.5 (2.1–5.9) 2.2 (1.3–4.2) 2.1 (0.2–12.4)c 0.045
  Median 2.9 1.9 2.0  
Hospital stay     
  Mean days (range) 32.5 (12–83) 9.6 (5–20) 7.4 (4–112) 0.552
  Median 17.5 8.5 7  
Complications     
 Any complication 3 (75 %) 5 (63 %) 156 (15.6 %) <0.001
 Bleeding-related complication     
  Major bleeding 1 (25 %) 1 (13 %) 26 (2.6 %) 0.041
  Minor bleeding 2 (50 %) 1 (13 %) 5 (0.5 %) <0.001
  Neuropraxia due to hematoma 0 0 0 NAd
  Evacuation of hematoma 0 0 1 (0.1 %) NAd
 Thromboembolic complication     
  Arterial thromboembolism 0 0 9 (0.9 %) 1.000
  Deep venous thrombosis 0 0 13 (1.3 %) 1.000
  Pulmonary embolism 0 0 5 (0.5 %) 1.000
 Heparin-induced thrombocytopenia 0 0 0 NAd
 Infected TKA 1 (25 %) 1 (13 %) 8 (0.8 %) 0.006
 Death 0 0 4 (0.4 %) 1.000
  1. aTwenty-two values unknown
  2. bThree values unknown
  3. cTwenty-five values cannot be calculated
  4. dNot applicable, number too small to perform statistics