Efficacy of steroid addition to multimodal cocktail periarticular injection in total knee arthroplasty: a meta-analysis

Table 1 Details on the included studies in the meta-analysis

Author	Year of publication	Sample size	Patient mean age	Sex (M/F)	BMI	Steroid/control group	Drain/blocks/anesthesia	Cocktail	Steroid Used	Administration Method	Type of Knee arthroplasty	Other intervention protocol
Kwon	2014	76	69.3	0/76	25.9	76/76	?/none/SA	10 mg morphine, 300 mg ropivacaine,30 mg ketorolac, 300 μg of 1:1000 epinephrine	40 mg Triamcinolone	SLIA IAPC	Cemented TKA	Preoperative celecoxib, ultracet,pregabalin
											Unresurfaced patella	Postoperative PCA
Yue	2013	72	69.75	8/64	25.685	36/36	All drains/none/GA	0.75 % ropivacaine 30 ml, 1:1000 adrenaline 0.5 ml	7 mg Betamethasone	SLIA IAPC	TKA(unclassified)
												Postoperative PCA, celecoxib
Ikeuchi	2014	40	76.5	6/34	?	20/20	All drains/none/GA	20 ml of 0.75 % ropivacaine, 400 mg of isepamicin	6.6 mg Dexamethasone	Peri-articular tissues	Cemented TKA
											Unresurfaced patella	Postoperative PCA, loxoprofen
Chia	2013	127	66.93	?	31.15	84/43	None/none/SA	0.2 % ropivacaine and 100 ml 1:1000 adrenaline	Triamcinolone	SLIA IAPC	Cemented TKA,
									40 mg in subgroup1, 80 mg in subgroup2		Resurfaced patella	Postoperative celecoxib
Seah	2011	100	66.65	?	27	50/50	?/none/SA or GA	0.5 ml/kg of 1:200,000 epinephrine and 0.5 % bupivacaine	40 mg of Triamcinolone	SLIA IAPC	Cemented TKA,
												Postoperative PCA
Christensen	2009	76	65.508	23/53	33.9	39/37	?/FNB/GA	80 mg of bupivacaine, 4 mg morphine, 300 mg epinephrine, 100 mg clonidine, 750 mg cefuroxime	40 mg Methylprednisolone	SLIA IAPC	TKA(unclassified)	Preoperative elecoxib, oxycodone or acetaminophen

SA Spinal Anesthesia, GA General Anesthesia, SLIA IAPC, Systematic Infiltration Including Anterior and Posterior Capsule, TKA Total knee Arthroplasty, PCA Patient Controlled Analgesia, FNB, Femoral Nerve Block, ? Unknown

ISSN: 1749-799X