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Table 7 Semi-quantitative histopathological analysis of the inflammatory reaction (results)

From: Osteochondral regeneration with a novel aragonite-hyaluronate biphasic scaffold: up to 12-month follow-up study in a goat model

Time period Group Polymorphonuclear cells Lymphocytes Plasma cells Macrophages Giant cells/osteoclasts Fibrin Necrosis Osteolysis Neovessels
6 months Agili-C Mean 0.0 0.6 0.0 1.3 1.0 0.9 0.0 0.0 1.6
SD 0.0 0.5 0.0 0.5 0.0 0.8 0.0 0.0 0.5
Empty defect control Mean 0.0 0.0 0.0 0.3 1.0 1.0 0.0 0.0 1.7
SD 0.0 0.0 0.0 0.5 0.0 0.8 0.0 0.0 0.5
12 months Agili-C Mean 0.0 0.3 0.0 0.7 1.1 0.1 0.0 0.3 0.0
SD 0.0 0.7 0.0 0.9 0.3 0.3 0.0 0.7 0.0
Empty defect control Mean 0.0 0.3 0.0 0.7 1.3 0.3 0.0 0.0 1.0
SD 0.0 0.5 0.0 0.5 0.5 0.5 0.0 0.0 0.8
  1. Grading scale: 0: absence, 1: slight, 2: moderate, 3: marked, 4: severe SD: standard deviation