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Table 1 Effect of growth factors on protein synthesis in wounded mineralized osteoblasts.

From: The role of FGF-2 and BMP-2 in regulation of gene induction, cell proliferation and mineralization

Treatment Thymidine incorporation DPM × 103/ug protein
con 37.6 ±2.9
IGF-1 42.3 ± 4.2
FGF-2 114.3 ± 11
TGFβ 65.2 ± 12
PDGF 39.8 ± 7.2
BMP-2 41.5 ± 5.6
PGE2 84.1 ± 23.1
  1. Representative experiment showing the effects of IGF-1 (20 ng/ml), FGF-2 (2.0 ng/ml), TGFβ (2 ng/ml), PDGF (3 ng/ml), BMP-2 (100 ng), PGE2 (2 μg/ml) on proliferation/mg protein of MC3T3-E1 osteoblasts after 24 hours of treatment (n = 4).