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Table 1 The six drugs tested.

From: The effect of newer anti-rheumatic drugs on osteogenic cell proliferation: an in-vitro study

 

Drug

Concentration (μg/ml or nM)

Group 1

COX-2 inhibitor – Etoricoxib

4 μg/ml (1.1·10-5 M)

Group 2

Methotrexate

1 μg/ml (2.2·10-6 M)

Group 3

Dexamethasone

4 ng/ml

 

Etanercept (anti-TNF; rh soluble TNF-receptor)

1 μg/ml

 

Infliximab (anti-TNF; chimeric monoclonal antibody)

118 μg/ml

 

Leflunomide (pyrimidine synthesis inhibitor)

4 μg/ml (1.5·10-5 M)

  1. The drugs were combined between groups, but not within groups