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Fig. 5 | Journal of Orthopaedic Surgery and Research

Fig. 5

From: Exosomes derived from M2 macrophages prevent steroid-induced osteonecrosis of the femoral head by modulating inflammation, promoting bone formation and inhibiting bone resorption

Fig. 5

Osteogenesis and angiogenesis in vivo. (A) Representative three-dimensional reconstructed micro-CT images. (B) Quantitative analysis of micro-CT scanning. (C) Immunohistochemical staining of OCN. Bar graph showed the mean optical density of OCN. (D) New bone formation indicated by double fluorescence labelling with tetracycline and calcein. (E) Mineral apposition rate in different groups. (F) Representative images of micro-CT-based microangiography. (G) Quantitative analysis of vessel volume. (H) Immunohistochemical staining of VEGF. Bar graph showed the mean optical density of VEGF. N = 5 per group. *p < 0.05 compared with Normal group; #p < 0.05 compared with Model group

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X