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Fig. 4 | Journal of Orthopaedic Surgery and Research

Fig. 4

From: Exosomes derived from M2 macrophages prevent steroid-induced osteonecrosis of the femoral head by modulating inflammation, promoting bone formation and inhibiting bone resorption

Fig. 4

The expression of inflammatory mediators in different groups. (A) Serum expression level of TNF-α measured by ELISA. (B) Serum expression level of IL-6 measured by ELISA. (C) Serum expression level of IL-10 measured by ELISA. (D) The expression of TNF-α, IL-6 and IL-10 in the femoral heads of the different groups detected by immunohistochemical staining. Bar graphs showed the mean optical density of TNF-α, IL-6 and IL-10. N = 5 per group. *p < 0.05 compared with Normal group; #p < 0.05 compared with Model group

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