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Fig. 2 | Journal of Orthopaedic Surgery and Research

Fig. 2

From: Exosomes derived from M2 macrophages prevent steroid-induced osteonecrosis of the femoral head by modulating inflammation, promoting bone formation and inhibiting bone resorption

Fig. 2

The effects of M2-Exos on the proliferation and osteogenic differentiation of BMMSCs. (A) Proliferative potential of BMMSCs indicated by the CCK-8 assay. (B) Representative images of Alizarin red staining. (C) Quantitative analysis of alizarin red staining. (D) Representative images of ALP staining. (E) Quantitative analysis of ALP activity. (F) Expression of ALP, RUNX2, OCN and OPN mRNA measured by qRT-PCR. The Data are presented as the means ± SDs; N = 5; *p < 0.05

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