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Fig. 1 | Journal of Orthopaedic Surgery and Research

Fig. 1

From: MiR-98-5p plays suppressive effects on IL-1β-induced chondrocyte injury associated with osteoarthritis by targeting CASP3

Fig. 1

Expression levels of miR-98-5p and CASP3 in OA cartilage and OA cellular model. (A-C) ELISA assay was applied to determine the levels of IL-1β, IL-6 and TNF-α in OA-affected blood samples (n = 20) and control samples (n = 20). Quantitative real time PCR was used to detect the expression levels of miR-98-5p (D) and CASP3 mRNA (E) in cartilage samples of OA patients (n = 20) and control samples (n = 20). **p < 0.01 and ***p < 0.001 indicate OA versus Control; (F) Quantitative real time PCR was used to detect the expression levels of miR-98-5p and CASP3 mRNA in IL-1β-induced CHON-001 cells and controls. ***p < 0.001 indicates IL-1β versus Control

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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X