Fig. 7
From: circ_0029463 promotes osteoclast differentiation by mediating miR-134-5p/Rab27a axis
Overexpression of Rab27a abolish the effect of circ_0029463 knockdown on osteoclast differentiation. A, B Rab27a mRNA and protein expressions detected by RT-qPCR and western blot; C osteoclasts were observed after TRAP staining; D, E the biomarkers of osteoclasts, including NFATc1, TRAP and CTSK were detected using RT-qPCR and western blot. Data are expressed as mean ± standard deviation, cell experiments were repeated 3 times. *P < 0.05, when compared with mimic NC + oe-NC group; #P < 0.05, when compared with sh-circ_0029463 + oe-NC group