Fig. 6
From: circ_0029463 promotes osteoclast differentiation by mediating miR-134-5p/Rab27a axis
miR-134-5p negatively regulates Rab27a expression to mediate osteoclast differentiation. A, B Rab27a mRNA and protein expressions detected by RT-qPCR and western blot; C osteoclasts were observed after TRAP staining; D, E the biomarkers of osteoclasts, including NFATc1, TRAP and CTSK were detected using RT-qPCR and western blot. Data are expressed as mean ± standard deviation, cell experiments were repeated 3 times. *P < 0.05, when compared with mimic NC + oe-NC group; #P < 0.05, when compared with miR-134-5p mimic + oe-NC group