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Fig. 3 | Journal of Orthopaedic Surgery and Research

Fig. 3

From: circ_0029463 promotes osteoclast differentiation by mediating miR-134-5p/Rab27a axis

Fig. 3

circ_0029463 negatively regulates miR-134-5p expression. A Binding sites of circ_0029463 with miR-134-5p; B, C RT-qPCR detected the expression of miR-134-5p in patients with osteoporosis and osteoclasts, respectively; D, E RIP and dual-luciferase reporter gene assay both verified the regulation of circ_0029463 on miR-134-5p. Data are expressed as mean ± standard deviation, cell experiments were repeated 3 times. *P < 0.05, when compared with Control, mimic NC or IgG group

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