Correlation between vascular endothelial growth factor A gene polymorphisms and tendon and ligament injury risk: a systematic review and meta-analysis

Table 1 Main characteristics and quality score of studies included

References	Country	Ethnicity	Gender (F/M)	Cases	Controls								NOS score
References	Country	Ethnicity	Gender (F/M)	N	Age^a	Of cite	Diagnosis	Matching	N	Age^a	HWE	Healthy	NOS score
Cięszczyk et al. [27]	Poland	Caucasian	115/257	229	26 ± 4	ACL	Surgery	Age and Sex	143	24.2 ± 4.1	HWE	Yes	7
Shukla et al. [28]	India–United Kingdom	Indo-Pakistani	32/134	90	26.6 ± 6.2	ACL	Radiology or Surgery	Age and Sex	76	62.2 ± 5.7	HWE	Yes	7
Rahim et al.[29]	South Africa	Caucasian	SA 78/150	108	42.9 ± 13.6	Achilles Tendon	WHO	Age and Sex	120	37.3 ± 10.4	HWE	Yes	6
Rahim et al.[29]	United Kingdom	Caucasian	UK 84/133	87	45.2 ± 14.4	Achilles Tendon	WHO	Age and Sex	130	41.6 ± 11.6	HWE	Yes	6
Rahim et al.[30]	South Africa	Colored	36/162	98	24.5 ± 7.5	ACL	WHO	Age and Sex	100	27.4 ± 6.7	HWE	Yes	5
Rahim et al.[31]	South Africa	Caucasian	151/310	227	26.8 ± 11.0	ACL	WHO	Sex	234	29.3 ± 11.3	HWE	Yes	6
Lulińska-Kuklik et al. [19]	Poland	Caucasian	149/263	222	F 25 ± 4	ACL	Surgery	Sex	190	F 29 ± 2	HWE	Yes	7
Lulińska-Kuklik et al. [19]	Poland	Caucasian	149/263	222	M 26 ± 4	ACL	Surgery	Sex		M 25 ± 2	HWE	Yes	7

F female, M male, NA not available, ACL anterior cruciate ligament, WHO World Health Organization diagnostic criteria, HWE Hardy–Weinberg equilibrium, a mean ± SD, NA not available

ISSN: 1749-799X