Combined Systemic Immune-inflammatory Index (SII) and Geriatric Nutritional Risk Index (GNRI) predict survival in elderly patients with hip fractures: a retrospective study

Table 1 Clinical characteristics of study patients

Variable	Total, n = 597	Survival status		P value
Variable	Total, n = 597	Alive patients (507)	Dead patients (90)	P value
Age, years (Mean,SD)	77.55 ± 10.90	76.93 ± 11.24	81.04 ± 10.91	0.001
Age ≥ 80 years, n	291	236	55	0.011
Female, n	468	400	68	0.478
Hypertension, n	348	290	58	0.199
Diabetes, n	175	147	28	0.684
Cerebral disease, n	128	100	28	0.013
Heart disease, n	191	150	41	0.003
Charlson Comorbidities Index > 2, n	74	47	27	< 0.001
ASA > 2, n	344	276	68	< 0.001
Hip fracture type
Intertrochanteric, n	257	203	54
Neck, n	340	304	36	< 0.001
Length of stay, day (Mean, SD)	11.30 ± 9.24	10.28 ± 6.36	17.07 ± 17.39	< 0.001
Blood transfusion, n	227	169	58	< 0.001
Anemia, n	183	129	54	< 0.001
Albumin, × g/L (Mean, SD)	35.95 ± 4.05	36.36 ± 3.90	33.64 ± 4.12	< 0.001
NEU count, × 10⁹/L (Mean, SD)	7.03 ± 2.86	6.77 ± 2.65	8.50 ± 3.46	< 0.001
LYM count, × 10⁹/L (Mean, SD)	1.14 ± 0.51	1.14 ± 0.46	1.19 ± 0.70	0.370
PLT, × 10⁹/L (Mean, SD)	210.87 ± 75.45	205.19 ± 72.03	242.89 ± 86.014	< 0.001
Height, × CM (Mean, SD)	162.64 ± 7.85	162.61 ± 7.78	162.84 ± 8.26	0.977
Weight, × Kg (Mean, SD)	63.00 ± 11.28	63.52 ± 11.01	60.00 ± 12.30	0.023
GNRI (Mean, SD)	580.42 ± 61.41	586.93 ± 59.13	543.73 ± 61.42	< 0.001
SII (Mean, SD)	1521.34 ± 1047.00	1404.58 ± 931.38	2179.13 ± 1376.17	< 0.001
POCs, n	98	56	42	< 0.001
1-year death, n	90

ASA American Society of Anesthesiologists physical score, NEU neutrophil, LYM lymphocyte, PLT Platelet, GNRI Geriatric Nutritional Risk Index, SII Systemic Immune-inflammatory Index, POCs postoperative complications
Heart disease coronary heart disease, myocardial infarction and heart failure; Cerebral disease Alzheimer's disease, Parkinson's disease and a history of cerebral infarction

ISSN: 1749-799X