Fig. 5
From: PDK4 inhibits osteoarthritis progression by activating the PPAR pathway
PDK4 regulates the PPAR signaling pathway in IL-1β-induced chondrocytes. A Venn diagram of PDK4 co-expressed genes (top 1000) and OA-associated genes (top 2000). B KEGG enrichment analysis of common genes. C Western blot analysis was implemented to examine the expression of proteins related to the PPAR signaling pathway, including PPARA, PPARD, and ACSL1. ***P < 0.001 versus control group; ##P < 0.01 versus IL-1β + ov-NC group