Fig. 2
From: PDK4 inhibits osteoarthritis progression by activating the PPAR pathway
Through the MCODE algorithm and degree algorithm in CytoHubba plug-in to identify key genes in the PPI network. A Two significant modules identified based on MCODE analysis. The lines between the nodes represent the interactions between the genes. B The top 12 genes with the highest scores were filtered based on the degree algorithm in cytoHubba plug-in. The lines between the nodes represent the interactions between the genes. C PCA of the key genes. The axes PC1 and PC2 represent the first and second principal components, indicating the explanatory rate of potential variables for differences. Dots represent samples, and different colors signify distinct groupings. D Matrix correlation analysis of key genes