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Table 5 Comparison of wild-type and mutant biochemical indexes of LRP5 gene rs3736228 locus between normal bone mass group and abnormal bone mass group

From: Relationship between polymorphisms and mutations at rs7125942 and rs3736228 of LRP5 gene and bone metabolism in postmenopausal women

Variables

Normal bone mass

Abnormal bone mass

CC

CT/TT

CC

CT/TT

FPG (mmol/L)

6.70 ± 3.18

6.03 ± 2.34

6.77 ± 2.06

6.42 ± 1.65

HbA1C%

6.67 ± 1.36

6.36 ± 1.08

7.09 ± 1.34

6.78 ± 0.92

TG (mmol/L)

2.40 ± 1.94

2.33 ± 2.33

1.67 ± 0.99

1.58 ± 0.99

LDL (mmol/L)

3.23 ± 0.81

3.11 ± 0.81

 3.42 ± 0.99

 3.23 ± 0.95

HDL (mmol/L)

1.21 ± 0.35

1.40 ± 0.35

1.25 ± 0.32

1.24 ± 0.28

Ca (mmol/L)

2.26 ± 0.22

2.26 ± 0.06

2.27 ± 0.10

2.29 ± 0.09

P (mmol/L)

1.07 ± 0.10

1.14 ± 0.11

1.28 ± 1.25

1.05 ± 0.12

ALP (mmol/L)

78.95 ± 19.25

70.57 ± 14.59

 76.47 ± 21.11

76.00 ± 24.79

BMD (L1–L4)

1.23 ± 0.16

1.13 ± 0.09

0.89 ± 0.15

0.89 ± 0.11

BMD (Femoral neck)

0.90 ± 0.11

0.72 ± 0.47*

0.74 ± 0.11

0.73 ± 0.12

  1. *P < 0.05 compared with CC genotype