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Table 4 Comparison of wild-type and mutant biochemical indexes of LRP5 gene rs7125942 locus between normal bone mass group and abnormal bone mass group

From: Relationship between polymorphisms and mutations at rs7125942 and rs3736228 of LRP5 gene and bone metabolism in postmenopausal women

Variables

Normal bone mass

Abnormal bone mass

CC

CG

CC

CG

FPG (mmol/L)

6.78 ± 3.20

5.27 ± 0.85*

6.65 ± 1.95

6.39 ± 1.11

HbA1C%

6.68 ± 1.38

6.16 ± 0.62

6.93 ± 1.18

7.78 ± 1.43

TG (mmol/L)

2.46 ± 2.11

1.99 ± 1.63

1.65 ± 1.00

1.41 ± 0.43

LDL (mmol/L)

3.31 ± 1.04

2.41 ± 0.52*

3.32 ± 0.98

3.84 ± 0.75

HDL (mmol/L)

1.26 ± 0.38

1.26 ± 0.22

1.25 ± 0.30

1.26 ± 0.46

Ca (mmol/L)

2.26 ± 0.20

2.29 ± 0.08

2.28 ± 0.10

2.27 ± 0.05

P (mmol/L)

1.10 ± 0.10

1.07 ± 0.11

1.20 ± 1.00

1.12 ± 0.15

ALP (mmol/L)

76.52 ± 18.83

77.78 ± 18.43

76.58 ± 22.30

70.50 ± 3.32*

BMD (L1–L4)

1.21 ± 0.15

1.18 ± 0.15

0.88 ± 0.14

0.97 ± 0.11

BMD (Femoral neck)

0.85 ± 0.29

0.87 ± 0.13

0.73 ± 0.11

0.71 ± 0.10

  1. *P < 0.05 compared with CC genotype