Fig. 7
From: Inhibition of HOXD11 promotes cartilage degradation and induces osteoarthritis development
Cartilage staining and immunohistochemistry assay of SOX9 and HOXD11 expression. a and b H&E and SOFG were used to stain the cartilage and assess the cartilage damage (original magnification × 40). Scale bars: 500 μM. c and d Immunohistochemistry of SOX9 and HOXD11 in human normal and OA knee joint cartilage (original magnification × 400). Scale bars: 50 μM. e OARSI histological score of OA severity in normal and OA knee joint cartilage. f Quantification of proteoglycan loss in normal and OA knee joint cartilage. g and h SOX9, HOXD11-positive cells were quantified in normal and OA knee joint cartilage. *P < 0.05, **P < 0.01 versus control