Fig. 6
From: Inhibition of HOXD11 promotes cartilage degradation and induces osteoarthritis development
Overexpression of HOXD11 in OA cells reverses the effects. a The cultivated chondrocyte cells in 60 mm plates (magnification, × 100). Scale bars: 200 μM. b qRT-PCR was performed to evaluate HOXD11 mRNA expression. c CCK-8 was conducted to evaluate proliferation. d Flow cytometry was performed to evaluate cell apoptosis. e WB was performed to evaluate expression of SOX9 and COL2A1. f qRT-PCR was conducted to evaluate SOX9 and COL2A1 mRNA levels. g WB was used to quantify MMP13 and ADAMTS5 expression. h qRT-PCR was utilized to quantify MMP13 and ADAMTS5 mRNA levels. *P < 0.05, **P < 0.01 versus control or OA + vector