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Table 7 Types of techniques used to assess chondrogenesis of MSCs

From: The use of mesenchymal stem cells for cartilage repair and regeneration: a systematic review

Type of techniques

No. of studies (%)

References

Histology

87 (79%)

[48, 5053, 164, 168170, 173175, 177179, 181187, 191195, 197201, 204211, 213217, 219222, 226, 229, 230, 232238, 240248, 250, 252264, 267271]

Immunohistochemistry

78 (71%)

[48, 50, 52, 53, 168171, 173175, 178183, 185191, 193, 194, 197, 198, 201, 203205, 207, 212215, 217, 218, 220, 221, 224, 226, 228238, 241, 242, 244, 246248, 250259, 264, 265, 267271]

qPCR

70 (64%)

[53, 168, 169, 173, 174, 176, 178186, 188, 190, 192194, 196, 199, 200, 202205, 207209, 211, 214, 216220, 222232, 235, 236, 239, 240, 242, 246, 249251, 256, 258, 259, 261263, 265267, 269271]

Biochemical analysis

64 (58%)

[48, 5052, 164, 168, 170172, 176, 177, 179, 180, 182184, 188, 189, 191, 192, 197, 199, 200, 202, 204, 205, 209, 212, 214, 216219, 222224, 226, 227, 233240, 244, 245, 247249, 252, 254, 257, 260266, 268270]

Imaging (confocal, SEM, TEM)

24 (22%)

[52, 172, 176, 180, 185, 187, 194, 198, 208, 215217, 225, 226, 230, 232, 241, 242, 249, 252, 255, 262, 263, 265]

Mechanical testing

15 (14%)

[51, 52, 164, 169, 175, 193, 197, 207, 220, 245, 247, 248, 256, 257, 268]