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Table 3 Radiographic OA grading

From: The temporal effect of platelet-rich plasma on pain and physical function in the treatment of knee osteoarthritis: systematic review and meta-analysis of randomized controlled trials

Studies

Intervention

Kellgren Lawrence

Ahlbäck

0

I

II

III

IV

I

II

III

Cerza et al.[9]

PRP

 

21

24

15

    
 

HA

 

25

22

13

    

Duymus et al.[29]

PRP

  

22

11

    
 

HA

  

24

10

    
 

Ozone

  

23

12

    

Filardo et al.[17]

PRP

0–IV, Mean ± SD: 2.0 ± 1.1

   
 

HA

0–IV, Mean ± SD: 2.0 ± 1.1

   

Forogh et al.[30]a

PRP

  

7

17

    
 

CS

  

8

16

    

Görmeli et al.[31]

PRP

 

I–III, 26

13

   
 

PRP/S

HA

 

I–III, 30

I–III, 25

14

14

   
 

Placebo

 

I–III, 27

13

   

Li et al.[10]

PRP

 

6

2

4

3

   
 

HA

 

6

3

3

3

   

Montañez-Heredia et al.[35]

PRP

 

5

10

12

    

HA

 

2

9

15

    

Patel et al.[11] a

PRP1

PRP2

     

37

36

11

10

2

2

 

Placebo

     

25

18

3

Paterson et al.[32]

PRP

  

II–III, 12

    
 

HA

  

II–III, 11

    

Raeissadat et al.[33]

PRP

 

5

34

29

9

   
 

HA

 

0

29

23

10

   

Sánchez et al.[13]

PRP

     

45

32

12

 

HA

     

42

32

11

Smith et al.[34]

PRP

  

8

7

    
 

Placebo

  

10

5

    

Spaková et al.[14]

PRP

 

2

39

19

    
 

HA

 

2

37

21

    

Vaquerizo et al.[15]

PRP

  

14

26

8

   
 

HA

  

18

21

9

   
  1. SD standard deviation, PRP/S single-PRP injection followed by saline injections, PRP1 single-PRP injection, PRP2 twice PRP injections
  2. aThe number of knees rather than patients was reported
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Journal of Orthopaedic Surgery and Research

ISSN: 1749-799X