From: Bone regenerative medicine: classic options, novel strategies, and future directions
Bone graft | Advantages | Disadvantages |
---|---|---|
Autografts | Optimal osteogenic, osteoinductive, and osteoconductive properties; gold standard for bone grafting; without the risks of immunogenicity and disease transmission | Pain and morbidity in the donor site, limited quantity and availability, need for further surgery, hematoma, infection, the need for general sedation or anesthesia, longer operative time, and blood loss |
Allografts | Osteoinductive and osteoconductive properties, without donor site morbidity, possible with local anesthesia, high availability, easy handling | Lack of osteogenic properties, potential antigenic response and disease transmission, variable osteoinductivity, limited supply, loss of biologic and mechanical properties due to its processing, non-availability worldwide due to religious and financial concerns and increased cost |
Xenografts | Osteoinductive and osteoconductive properties, low cost, high availability | Lack of osteogenic properties, the risk of immunogenicity and transmission of infectious and zoonotic diseases, poor outcome |