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  1. Cyclops lesion is the second most common cause of extension loss after anterior cruciate ligament reconstruction. This study focused on the correlation between the anatomy of the intercondylar notch and the in...

    Authors: Krzysztof Ficek, Jolanta Rajca, Jerzy Cholewiński, Agnieszka Racut, Paweł Gwiazdoń, Krzysztof Przednowek and Grzegorz Hajduk
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:554
  2. Knee anthropometric characteristics were evaluated for different ethnicities; however, data from North African populations are deficient. The primary aim was to investigate the Egyptian knees’ anthropometric c...

    Authors: Mohammad Kamal Abdelnasser, Ahmed A. Khalifa, Micheal Bassem, Mohammed Anter Abdelhameed, Mahmoud Faisal Adam, Hatem M. Bakr and Yaser E. Khalifa
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:552
  3. Trampoline-related fractures of the proximal tibial metaphysis are common in children and have been linked to subsequent valgus deformity of the tibia. The purpose of this study was to investigate the characte...

    Authors: Changhoon Jeong, Sang Uk Lee, Hyun Gyun Kim and Sun Young Joo
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:551
  4. Lumbar spinal stenosis (LSS) is a common degenerative condition of the spine that causes back pain radiating to the lower extremity. Surgical treatment is indicated to treat progressive radical symptoms. Obesi...

    Authors: Henni Myllykangas, Leena Ristolainen, Heikki Hurri, Jouni Lohikoski, Hannu Kautiainen, Ville Puisto, Heikki Österman and Mikko Manninen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:550
  5. The aim of this study was to quantify the incidence of and identify independent risk factors for decreased range of motion (ROM) of the knee joint after surgery for closed tibial plateau fractures in adults.

    Authors: Junyong Li, Junzhe Zhang, Kuo Zhao, Yanbin Zhu, Hongyu Meng, Zhucheng Jin, Dandan Ye, Wei Chen and Yingze Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:549
  6. Risk factors for the severity of patellofemoral osteoarthritis (PFOA) are poorly understood. This research aims to evaluate the association between patellofemoral joint (PFJ) morphology and alignment with the ...

    Authors: Yike Dai, Heyong Yin, Chongyang Xu, Hongrui Zhang, Ai Guo and Naicheng Diao
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:548
  7. Chronic ruptures, ruptures following total knee arthroplasty (TKA), and re-ruptures of the quadriceps tendon (QT) are rare. A systematic review of the current literature was conducted on their treatment and ou...

    Authors: Francesco Oliva, Emanuela Marsilio, Filippo Migliorini and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:547
  8. Tranexamic acid (TXA) has shown significant reductions in blood loss and transfusion rates in total knee arthroplasty (TKA). However, the optimal administration route continues to be debated. The aim of this t...

    Authors: Hui-ming Peng, Wei Wang, Jin Lin, Xi-sheng Weng, Wen-wei Qian and Wen-da Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:546
  9. Distal humerus fractures (DHFs) constitute one-third of elbow fractures approximately. In this study, we aim to define and analyze the fracture lines and morphological features of DHFs using mapping technique.

    Authors: Chao Wang, Yong Zhu, Haitao Long, Zhangyuan Lin, Ruibo Zhao, Buhua Sun, Shushan Zhao and Liang Cheng
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:545
  10. We aimed to evaluate risk factors and develop a nomogram for reoperation after internal fixation of nondisplaced femoral neck fractures (FNFs) in elderly patients.

    Authors: Jian Zhu, Hongzhi Hu, Xiangtian Deng, Yiran Zhang, Xiaodong Cheng, Zhanchao Tan, Yanbin Zhu and Yingze Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:544
  11. Focal chondral defects of the knee are common. Several surgical techniques have been proposed for the management of chondral defects: microfractures (MFX), osteochondral autograft transplantation (OAT), autolo...

    Authors: Filippo Migliorini, Jörg Eschweiler, Hanno Schenker, Alice Baroncini, Markus Tingart and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:543
  12. Pain catastrophizing and self-efficacy are useful for predicting pain; these are associated with pain intensity and facilitate evaluation of psychological factors. However, it remains unclear whether the effec...

    Authors: Junya Hirata, Minori Tomiyama, Yasuhiro Koike, Manabu Yoshimura and Keiko Inoue
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:542
  13. Ankle-subtalar joint complex instability is not uncommonly presented in the clinic, but symptoms and signs similar to other conditions can easily lead to its misdiagnosis. Due to the lack of appropriate animal...

    Authors: Peixin Liu, Kaiwen Chen, Shuo Wang, Chunzhuo Hua, Hongtao Zhang and Jia Yu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:541
  14. In-brace correction and brace compliance with thoraco-lumbo-sacral orthotic (TLSO) braces are associated with successful treatment of adolescent idiopathic scoliosis (AIS). This paper compares patients who had...

    Authors: Isabel Alvarez, Kiley Poppino, Lori Karol and Amy L. McIntosh
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:540
  15. The rotator cuff undergoes natural degeneration with age, leading to age-related rotator cuff tear; however, the precise mechanism remains unclear. Transforming growth factor-beta (TGF-β) concentrations rise w...

    Authors: Ryo Tazawa, Kentaro Uchida, Tomonori Kenmoku, Mitsufumi Nakawaki, Kyoko Muneshige, Daisuke Ishii, Gen Inoue and Masashi Takaso
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:539
  16. Fracture of the medial malleolus is one of the most frequent injuries treated surgically; however, the classification of the fracture has not attracted much attention and a good classification system is still ...

    Authors: Fangke Hu, Guoyun Bu, Jun Liang, Haijing Huang and Jinquan He
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:538
  17. Musculoskeletal disorders, especially in the feet, are common in people with Down syndrome (DS). Evaluation of podiatric footprints is important to prevent and manage orthopedic symptoms. The reliability of a ...

    Authors: Lourdes Gutiérrez-Vilahú and Myriam Guerra-Balic
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:537
  18. The prevalence of anaemia in patients planned for total hip and knee arthroplasty is about 20%. Optimising pre-operative haemoglobin levels by iron supplementation has been shown to decrease transfusion rates,...

    Authors: Viju Daniel Varghese, David Liu, Donald Ngo and Suzanne Edwards
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:536
  19. Free flaps have been a useful modality in the management of lower extremity osteomyelitis particularly in limb salvage. This study aimed to determine the factors affecting the outcome of free flap reconstructi...

    Authors: Duy Quang Thai, Yeon Kyo Jung, Hyung Min Hahn and Il Jae Lee
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:535
  20. Lumbar disc herniation (LDH) is a common problem. When surgical treatment is required, the intervention is typically decompression without fusion. Successful return-to-work (RTW) is a standard expectation with...

    Authors: Lauren A. Protzer, Steven D. Glassman, Praveen V. Mummaneni, Mohamad Bydon, Erica F. Bisson, Mladen Djurasovic and Leah Y. Carreon
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:534
  21. Osteoporosis affects mostly postmenopausal women, leading to deterioration of the microarchitectural bone structure and low bone mass, with an increased fracture risk with associated disability, morbidity and ...

    Authors: Filippo Migliorini, Nicola Maffulli, Giorgia Colarossi, Jörg Eschweiler, Markus Tingart and Marcel Betsch
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:533
  22. The current surgical treatment of choice is the combination surgical technique, involving tibial intramedullary fixation to maintain the mechanical axis and mechanical stability of tibial pseudarthrosis. In tr...

    Authors: Yaoxi Liu, Ge Yang, Guanghui Zhu, Qian Tan, Jiangyan Wu, Kun Liu, Jin Tang and Haibo Mei
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:532
  23. Volar locking plating remains a popular method for the surgical management of distal radius fractures. Dorsal metaphyseal comminution (DMC) is a common fracture pattern which weakens the stability during fract...

    Authors: Xue-yang Gui, Zhao-hui Cheng, Hong-fei Shi, Yi-xin Chen, Jin Xiong, Jun-fei Wang, Xu-sheng Qiu and Zi-tao Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:530
  24. To develop the novel self-reported spine functional scale (SSFS) and conduct reliability and validity analysis, so that the public can better understand their own spine function in a more simple and scientific...

    Authors: Wei Li, Jie Ding, Xiujuan Hao, Wenjun Jiang, Hongqiang Song, Yanming Zhang and Yan Tan
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:529
  25. External fixator (EF) is a popular choice for open tibial fractures, but pin tract infection (PTI) and refracture are common complications. Elastic stable intramedullary nail (ESIN) has been reported in the tr...

    Authors: Pan Hong, Saroj Rai, Xin Tang, Ruikang Liu and Jin Li
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:528
  26. Preexisting severe cervical spinal cord compression is a significant risk factor in cervical hyperextension injury, and the neurological function may deteriorate after a slight force to the forehead. There are...

    Authors: Jian-jie Wang, Meng-lei Xu, Hui-zi Zeng, Liang-dong Zheng, Shi-jie Zhu, Chen Jin, Zhi-li Zeng, Li-ming Cheng and Rui Zhu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:527
  27. This study compared the failure load of the femoral insertion site of the anterior cruciate ligament between different portions and knee flexion angles.

    Authors: Shohei Yamauchi, Kyohei Ishibashi, Eiji Sasaki, Shizuka Sasaki, Yuka Kimura and Yasuyuki Ishibashi
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:526
  28. Postmenopausal osteoporosis is characterized by an imbalance of bone resorption exceeding bone formation, resulting in a net loss of bone mass. Whether a menopause-related excess of iron contributes to the dev...

    Authors: Lu-lin Liu, Gong-wen Liu, Hui Liu, Kai Zhao and You-jia Xu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:525
  29. To investigate the necessity of nonstructural or structural intraarticular bone grafting in atlantoaxial facet joints via a posterior approach and the influence by the presence of basilar invagination (BI).

    Authors: Jun Zhu, Jian Wu, Keyu Luo, Zhong Wang, Huaijian Jin, Yufei Jin, Yingbo Wang, Mingyong Liu and Peng Liu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:524
  30. Osteosarcoma is one of the most common malignant neoplasms in children and adolescents. Studies have shown that metabolism-related pathways are vital for the development and metastasis of osteosarcoma. Long no...

    Authors: Xingyin Chen, Zhengyun Ye, Pan Lou, Wei Liu and Ying Liu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:523
  31. To explore the feasibility of sacral-2-alar (S2-alar) screw placement by measuring the length, diameter, and angle of the screw trajectory on computed tomography (CT).

    Authors: Yulin Zhao, Baisheng Yuan, Yijun Han and Binglei Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:522
  32. The aim of this study was to evaluate the influence of antirheumatic drug treatment on knee function of stiff knee patients after total knee arthroplasty (TKA).

    Authors: Cheng-Qi Jia, Xiao-Rui Guan, Zhi-Lai Zhao, Ji-Ying Chen and Xiang Li
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:521
  33. To evaluate the efficacy of ultra-early rehabilitation on elbow function after Slongo’s external fixation for supracondylar humeral fractures in older children and adolescents.

    Authors: Man He, Qian Wang, Jingxin Zhao and Yu Wang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:520
  34. Nontraumatic osteonecrosis of the femoral head (NONFH) is a devastating disease, and the risk factors associated with progression into collapse after core decompression (CD) remain poorly defined. Therefore, w...

    Authors: En-Ze Zhao, Zun-Han Liu, Wei-Nan Zeng, Zi-Chuan Ding, Zhen-Yu Luo and Zong-Ke Zhou
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:519
  35. The surgical outcomes of anterior cervical discectomy and fusion (ACDF) in female patients according to menopausal status remain unclear. The objective of this study was to investigate the differences in these...

    Authors: Xing-jin Wang, Hao Liu, Jun-bo He, Quan Gong, Ying Hong, Xin Rong, Chen Ding, Bei-yu Wang, Yi Yang and Yang Meng
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:518
  36. Currently, patient-reported outcome measures (PROMs) are the standard instruments used to compare arthroplasty results. Goodman et al. recently published a well-constructed scale with excellent psychometric pr...

    Authors: Julián Brañes, Maximiliano Barahona, Sebastián Carvajal, Rodrigo Wulf and Cristián Barrientos
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:517
  37. Musculoskeletal conditions are highly prevalent, and knee OA is most common. Current treatment modalities have limitations and either fail to solve the underlying pathophysiology or are highly invasive. To add...

    Authors: Ashim Gupta, Nicola Maffulli, Hugo C. Rodriguez, R. Justin Mistovich, Kristin Delfino, Craig Cady, Anne-Marie Fauser, Echo D. Cundiff, Marte A. Martinez and Anish G. Potty
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:514
  38. Direct anterior approach (DAA) has several advantages including shorter length of hospital stay, faster recovery, and better functional outcome while this approach may cause damage to the lateral femoral cutan...

    Authors: Ong-art Phruetthiphat, Vasin Sangthumprateep, Songpol Trakulngernthai, Noppadol Aegakkatajit, Thanainit Chotanaphuti and Malee Chanpoo
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:513
  39. Developmental dysplasia of the hip (DDH) is a highly prevalent hip disease among children. However, its pathogenesis remains unclear. MicroRNAs (miRNA) are important regulators of cartilage development. In a p...

    Authors: Rui Ding, Xijuan Liu, Jian Zhang, Jinghong Yuan, Sikuan Zheng, Xigao Cheng and Jingyu Jia
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:512
  40. Cannulated screws (CS) are one of the most widely used treatments for femoral neck fracture, however, associated with high rate of complications. In this study, we designed a new type of cannulated screws call...

    Authors: Kai Ding, Weijie Yang, Jian Zhu, Xiaodong Cheng, Haicheng Wang, Du Hao, Song Yinuo, Yanbin Zhu, Yingze Zhang, Wei Chen and Qi Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:511
  41. The occurrence of chemoresistance is a common problem in tumor treatment. Circular RNA (circRNA) has been confirmed to be related to tumor chemoresistance. However, the role and the underlying molecular mechan...

    Authors: Yumei Bai, Yanghua Li, Juan Bai and Yumei Zhang
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:510
  42. Pertrochanteric fractures of the femur in the elderly are very common. As the average age of the population increases, the incidence of such fractures also raises, resulting in high healthcare costs. The type ...

    Authors: Giuseppe Gargano, Nicola Poeta, Francesco Oliva, Filippo Migliorini and Nicola Maffulli
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:509
  43. Improved oncological and surgical measures now enable curative treatment of malignant lower extremity tumors in majority of cases. Complication rates associated with surgical resection of lower extremity tumor...

    Authors: Moritz von Salis-Soglio, Mohamed Ghanem, Christian Lycke, Andreas Roth and Georg Osterhoff
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:508
  44. The anterior cruciate ligament (ACL) has a key role as a dynamic stabilizer of the knee joints, and ACL dysfunction caused by traumatic or degenerative rupture accelerates osteoarthritis progression. Thus, it ...

    Authors: Masaru Idota, Shinya Ishizuka, Hideki Hiraiwa, Satoshi Yamashita, Hiroki Oba, Yusuke Kawamura, Takefumi Sakaguchi, Takahiro Haga, Takafumi Mizuno, Itaru Kawashima, Kanae Kuriyama and Shiro Imagama
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:507
  45. Open reduction internal fixation (ORIF) has long been the conventional procedure for managing displaced patella fracture. This surgical approach has certain drawbacks, which might affect clinical outcomes and ...

    Authors: Chun-Hong Lo and Chih-Hwa Chen
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:506
  46. Dimensional measurements have been implemented on a variety of entities in morphological studies of the sub-axial cervical vertebral endplate. Despite great progress, little information between the mid-sagitta...

    Authors: Long Wang, Hao T. Luo, Wei Lu, Xing Bo Cai, Chen Yu and Sheng Lu
    Citation: Journal of Orthopaedic Surgery and Research 2021 16:503

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