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  1. Sickle cell anemia (SCA) is a common genetic disease in Nigeria. Past studies from West Africa focused on isolated aspects of its medical and surgical presentations. To the best of our knowledge, the musculo-s...

    Authors: Rufai A Balogun, Dike C Obalum, Suleiman O Giwa, Thomas O Adekoya-Cole, Chidiebere N Ogo and George O Enweluzo

    Citation: Journal of Orthopaedic Surgery and Research 2010 5:2

    Content type: Research article

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  2. Matrix metalloproteinase (MMPs) synthesized and secreted from connective tissue cells have been thought to participate in degradation of the extracellular matrix. Increased MMPs activities that degrade proteog...

    Authors: Korakot Nganvongpanit, Patama Chaochird, Puntita Siengdee, Peraphan Pothacharoen, Kasisin Klunklin, Siriwadee Chomdej, Supamit Mekchay and Prachya Kongtaweelert

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:45

    Content type: Research article

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  3. Severe symptomatic osteoarthritis in young and active patients with pre-existing deficiency of the anterior cruciate ligament and severe functionally instability is a difficult subgroup to manage. There is con...

    Authors: Srikrishna RSR Krishnan and Ray Randle

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:43

    Content type: Research article

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  4. As longevity of cementless femoral components enters the third decade, concerns arise with long-term effects of fixation mode on femoral bone morphology. We examined the long-term consequences on femoral remod...

    Authors: Brad Ellison, Nicholas A Cheney, Keith R Berend, Adolph V Lombardi Jr and Thomas H Mallory

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:42

    Content type: Research article

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  5. Ankle sprains are very common injuries seen in the athletic and young population. Majority of patients will improve with a course of rest and physical therapy. However, with conservative management about twent...

    Authors: Xinning Li, Timothy J Lin and Brian D Busconi

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:41

    Content type: Technical Note

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  6. Dislocation of the shoulder is the commonest of all large joint dislocations. Inferior dislocation constitutes 0.5% of all shoulder dislocations. It characteristically presents with overhead abduction of the a...

    Authors: S Saseendar, Dinesh K Agarwal, Dilip K Patro and Jagdish Menon

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:40

    Content type: Case report

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  7. Controversies exist regarding the indications for unicompartmental knee arthroplasty. The objective of this study is to report the mid-term results and examine predictors of failure in a metal-backed unicompar...

    Authors: Thorsten M Seyler, Michael A Mont, Lawrence P Lai, Jipan Xie, David R Marker, Michael G Zywiel and Peter M Bonutti

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:39

    Content type: Research article

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  8. Total knee arthroplasty represents a common orthopedic surgical procedure. Achieving proper alignment of its components with the predrilled patellar and tibial peg holes prior to polymerization of the bone cem...

    Authors: William B Lutes, Michael A Flierl, Michael R Dayton and Steven J Morgan

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:38

    Content type: Technical Note

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  9. Restoration and maintenance of the plateau surface are the key points in the treatment of tibial plateau fractures. Any deformity of the articular surface jeopardizes the future of the knee by causing osteoart...

    Authors: Benoit Benoit, Zhim Fouad, George-Henri Laflamme, Dominique Rouleau and G Yves Laflamme

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:37

    Content type: Research article

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  10. Most studies comparing the Risser staging for skeletal maturity are representing the American or European standards which are not always applicable to Asian population who have relatively less height and body ...

    Authors: Hitesh N Modi, Chetna H Modi, Seung Woo Suh, Jae-Hyuk Yang and Jae-Young Hong

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:36

    Content type: Research article

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  11. Treatment of distal tibial intra-articular fractures is challenging due to the difficulties in achieving anatomical reduction of the articular surface and the instability which may occur due to ligamentous and...

    Authors: Elias S Vasiliadis, Theodoros B Grivas, Spyridon A Psarakis, Evangelos Papavasileiou, Angelos Kaspiris and Georgios Triantafyllopoulos

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:35

    Content type: Research article

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  12. Development of hip adductor, tensor fascia lata, and rectus femoris muscle contractures following total hip arthroplasties are quite common, with some patients failing to improve despite treatment with a varie...

    Authors: Anil Bhave, Michael G Zywiel, Slif D Ulrich, Mike S McGrath, Thorsten M Seyler, David R Marker, Ronald E Delanois and Michael A Mont

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:34

    Content type: Research article

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  13. Treatment of ruptured Achilles tendons currently constitutes of conservative early functional treatment or surgical treatment either by open or minimal invasive techniques. We hypothesize that an experimental ...

    Authors: Robert Kraemer, Johan Lorenzen, Robert Rotter, Peter M Vogt and Karsten Knobloch

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:32

    Content type: Research article

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  14. Pasteurized bone grafting is used following the excision of a bone tumor for the purpose of eliminating neoplastic cells while preserving bone-inducing ability. In the hopes of guaranteeing the most favourable...

    Authors: Tatsuya Yoshida, Akio Sakamoto, Nobuaki Tsukamoto, Koichi Nakayama and Yukihide Iwamoto

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:31

    Content type: Research article

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  15. The treatment of an above knee amputee who has sustained a fracture of femoral neck is a challenge for both the orthopaedic surgeon and the rehabilitation team. We present a case of such a patient and discuss ...

    Authors: Leonid Kandel, Miguel Hernandez, Ori Safran, Isabella Schwartz, Meir Liebergall and Yoav Mattan

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:30

    Content type: Case report

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  16. Superior dislocation of the patella is an uncommon condition that mainly occurs in knees with a high patella and medial femorotibial degenerative arthritis. There are no previous reports of this condition occu...

    Authors: Xavier Cusco, Roberto Seijas, Oscar Ares, Jose R Cugat, Montserrat Garcia-Balletbo and Ramon Cugat

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:29

    Content type: Case report

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  17. Treatment of unstable thoracolumbar fractures is controversial regarding short or long segment pedicle screw fixation. Although long level fixation is better, it can decrease one motion segment distally, thus ...

    Authors: Hitesh N Modi, Kook Jin Chung, Il Woo Seo, Hoi Soo Yoon, Ji Hyo Hwang, Hong Kyun Kim, Kyu Cheol Noh and Jung Han Yoo

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:28

    Content type: Research article

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  18. Ectopic chondrogenesis and ossification were observed in a degenerative collagenase-induced calcific tendinopathy model and to a lesser extent, in a patellar tendon traumatic injury model. We hypothesized that...

    Authors: Pauline Po Yee Lui, Lai Shan Chan, Yau Chuk Cheuk, Yuk Wa Lee and Kai Ming Chan

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:27

    Content type: Research article

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  19. Asymptomatic local bone resorption of the tibia under the baseplate can occasionally be observed after total knee arthroplasty (TKA). Its occurrence is not well documented, and so far no explanation is availab...

    Authors: Bernardo Innocenti, Evelyn Truyens, Luc Labey, Pius Wong, Jan Victor and Johan Bellemans

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:26

    Content type: Research article

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  20. Surgery for disc herniations can be complicated by two major problems: painful degeneration of the spinal segment and re-herniation. Therefore, we examined an absorbable poly-glycolic acid (PGA) biomaterial, w...

    Authors: Aldemar A. Hegewald, Sven Knecht, Daniel Baumgartner, Hans Gerber, Michaela Endres, Christian Kaps, Edgar Stüssi and Claudius Thomé

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:25

    Content type: Research article

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  21. We present a case of a Salter-Harris II injury to the proximal tibia associated with both vascular compromise and compartment syndrome. The potential complications of this injury are limb threatening and the n...

    Authors: Nicholas D. Clement and Anukul Goswami

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:23

    Content type: Case report

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  22. Exercise during postnatal development plays a key role in determining adult bone mass and reducing the risk of fracture and osteoporosis later in life. However, the relationship between mechanically-induced os...

    Authors: Jeffrey H Plochocki

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:22

    Content type: Research article

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  23. Fractures of the clavicle comprise between 5% to10% of all fractures. Medial clavicular fractures are uncommon and are normally caused by high-energy trauma. A low impact mechanism of injury should raise suspi...

    Authors: Sheraz S Malik, Saiqah Azad, Shahbaz Malik and Caroline B Hing

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:21

    Content type: Case report

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  24. Percutaneous endoscopic lumbar discectomy is a relatively new technique. Very few studies have reported the clinical outcome of percutaneous endoscopic discectomy in terms of quality of life and return to work.

    Authors: Chan WB Peng, William Yeo and Seang B Tan

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:20

    Content type: Research article

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  25. Apoptosis of osteoblasts and osteoclasts regulates bone homeostasis. Skeletal injury in humans results in 'angiogenic' responses primarily mediated by vascular endothelial growth factor(VEGF), a protein essent...

    Authors: John Street and Brian Lenehan

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:19

    Content type: Research article

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  26. Fat Embolism is a complication of long bone fractures, intramedullary fixation and joint arthroplasty. It may progress to fat embolism syndrome, which is rare but involves significant morbidity and can occasio...

    Authors: R Yoga, JC Theis, M Walton and W Sutherland

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:18

    Content type: Research article

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  27. Disease modifying anti-rheumatic drugs (DMARDs) may interfere with bone healing. Previous studies give conflicting advice regarding discontinuation of these drugs in the peri-operative setting. No consensus ex...

    Authors: Ajay Malviya, Jan Herman Kuiper, Nilesh Makwana, Patrick Laing and Brian Ashton

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:17

    Content type: Research article

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  28. Lag screw cut-out failure following fixation of unstable intertrochanteric fractures in osteoporotic bone remains an unsolved challenge. This study tested if resistance to cut-out failure can be improved by us...

    Authors: George K Kouvidis, Mark B Sommers, Peter V Giannoudis, Pavlos G Katonis and Michael Bottlang

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:16

    Content type: Research article

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  29. Musculoskeletal disorders specially knee osteoarthritis are the most common causes of morbidity in old patients. Disturbance of the mechanical axis of the lower extremity is one of the most important causes in...

    Authors: Farzad Omidi-Kashani, Ibrahim G Hasankhani, Mahdi Mazlumi and Mohamad H Ebrahimzadeh

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:15

    Content type: Research article

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  30. This study was performed to evaluate the results of negative pressure wound therapy (NPWT) in patients with open wounds in the foot and ankle region.

    Authors: Hyun-Joo Lee, Joon-Woo Kim, Chang-Wug Oh, Woo-Kie Min, Oog-Jin Shon, Jong-Keon Oh, Byung-Chul Park and Joo-Chul Ihn

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:14

    Content type: Research article

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  31. Traumatic chondral lesions of the knee are common in football and rugby players. The diagnosis is often confirmed by arthroscopy which can be therapeutic by performing microfracture. Prospective information ab...

    Authors: Masoud Riyami and Christer Rolf

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:13

    Content type: Research article

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  32. Heterotopic ossification (HO) is defined as the process by which trabecular bone forms outside of the skeletal structure, occupying space in soft tissue where it does not normally exist. The current popular pr...

    Authors: Evan O Baird and Qian K Kang

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:12

    Content type: Review

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  33. The per-operative assessment of primary stem stability may help to improve the performance of total hip replacement. Vibration analysis methods have been successfully used to assess dental implant stability, t...

    Authors: Leonard C Pastrav, Siegfried V N Jaecques, Ilse Jonkers, Georges Van der Perre and Michiel Mulier

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:10

    Content type: Research article

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  34. Non-steroidal anti-inflammatory drugs (NSAID) are commonly used in the treatment of tendinopathies such as tendonitis and tendinosis. Despite this, little is known of their direct actions on tendon-derived cel...

    Authors: Emad Mallick, Nanette Scutt, Andy Scutt and Christer Rolf

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:9

    Content type: Research article

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  35. Increase in hip intra-capsular pressure has been implicated in various hip pathologies, such as avascular necrosis complicating undisplaced femoral neck fracture. Our study aimed at documenting the relationshi...

    Authors: Chi-Hung Yen, Hon-Bong Leung and Paul Yun-Tin Tse

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:8

    Content type: Research article

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  36. Despite the numerous in-vitro studies on the mechanical properties and simulated injury mechanisms of the anterior talofibular ligament (ATFL) and calcaneofibular ligament (CFL), the in-vivo biomechanical beha...

    Authors: Richard J de Asla, Michal Kozánek, Lu Wan, Harry E Rubash and Guoan Li

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:7

    Content type: Research article

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  37. Tissue-engineered bone may be developed by seeding the cells capable of both osteogenesis and vascularization on biocompatible composite scaffolds. The current study investigated the performance of mice bone m...

    Authors: Haiying Yu, Paul H Wooley and Shang-You Yang

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:5

    Content type: Research article

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  38. The decision, whether to amputate or reconstruct a mangled extremity remains the subject of extensive debate since multiple factors influence the decision.

    Authors: Anastasios V Korompilias, Alexandros E Beris, Marios G Lykissas, Marios D Vekris, Vasileios A Kontogeorgakos and Panayiotis N Soucacos

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:4

    Content type: Research article

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  39. A variety of knee injuries and pathologies may cause a deficit in knee proprioception which may increase the risk of reinjury or the progression of disease. Stochastic resonance stimulation is a new therapy wh...

    Authors: Amber T Collins, J Troy Blackburn, Chris W Olcott, Douglas R Dirschl and Paul S Weinhold

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:3

    Content type: Research article

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  40. Anterior cruciate ligament (ACL) injury or reconstruction can cause knee impairments and disability. Knee impairments are related to quadriceps performance – accelerated reaction time (ART) – and disability to...

    Authors: Maria G Papandreou, Evdokia V Billis, Emmanouel M Antonogiannakis and Nikos A Papaioannou

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:2

    Content type: Research article

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  41. Thrombin related peptide (TP508) is a 23 amino-acid synthetic peptide that represents a portion of the receptor-binding domain of thrombin molecule. Previous studies have shown that TP508 can accelerate muscul...

    Authors: Brain M Hanratty, James T Ryaby, Xiao-Hua Pan and Gang Li

    Citation: Journal of Orthopaedic Surgery and Research 2009 4:1

    Content type: Research article

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  42. A cross-sectional study was performed to describe the upper limb deformity and function in cerebral palsy patients and to determine the correlation of deformity, spasticity, motor control, and sensation to han...

    Authors: Karlen Law, Ellen Y Lee, Boris Kwok-Keung Fung, Lam Shuk Yan, Paata Gudushauri, Kwan Wing Wang, Josephine Wing-Yuk Ip and Shew Ping Chow

    Citation: Journal of Orthopaedic Surgery and Research 2008 3:52

    Content type: Research article

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  43. Hip fracture is associated with pronounced morbidity and excess mortality in elderly women with postmenopausal osteoporosis. Many drugs have been developed to treat osteoporosis and to reduce the risk of osteo...

    Authors: Yoshinari Nakamura, Masatoshi Naito, Kazuo Hayashi, Abbas Fotovati and Samah Abu-Ali

    Citation: Journal of Orthopaedic Surgery and Research 2008 3:51

    Content type: Research article

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