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  1. To investigate the efficacy and safety of allograft and hydroxyapatite (HA) as substitutes for autograft in anterior cervical discectomy and fusion (ACDF).

    Authors: Changsheng Yang, Wentao Zhuo, Qingchu Li, Caiqiang Huang, Huibo Yan and Dadi Jin

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:123

    Content type: Research article

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  2. Pelvic bone fractures are one of the biggest challenges faced by trauma surgeons. Especially, the presence of bleeding and hemodynamic instability features is associated with high morbidity and mortality in pa...

    Authors: Myoung Jun Kim, Jae Gil Lee, Eun Hwa Kim and Seung Hwan Lee

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:122

    Content type: Research article

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  3. Although efficacy is related to many factors, the surgical approach is one of the most important intervention factors for complex ankle fractures. Ankle fractures involving the distal tibial plafond frequently...

    Authors: Tong Liu, Yiheng Cheng and Wenqing Qu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:120

    Content type: Research article

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  4. Although researchers have adopted various methods for the resection and reconstruction of periacetabular tumors, the total incidence rate of complications remains high. Aiming for preserving the acetabulum and...

    Authors: Chunzhi Yi, Jiaqian Zheng, Ruoyu Li, Yun Lan, Mincong He, Jieqing Lai, Tianan Guan, Fengxiang Pang, Zongquan Mo, Peng Chen, Yue Li, Nannan Zhou, Xingfu Yang and Bin Fang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:119

    Content type: Research article

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  5. Despite tibial plateau fractures are often associated with meniscal tears, the association between meniscal tears and Schatzker classification remains unclear. The purpose of this study was to assess the frequ...

    Authors: Xiangtian Deng, Hongzhi Hu, Yuchuan Wang, Decheng Shao and Yingze Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:117

    Content type: Research article

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  6. Long non-coding RNA heart and neural crest derivatives expressed 2-antisense RNA 1 (HAND2-AS1) was found to be elevated in rheumatoid arthritis (RA) fibroblast-like synoviocytes (RA-FLSs). However, whether HAN...

    Authors: Yuhua Su, Yajing Liu, Chao Ma, Chunxiao Guan, Xiufen Ma and Shan Meng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:116

    Content type: Research article

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  7. An amendment to this paper has been published and can be accessed via the original article.

    Authors: Sujin Kang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:115

    Content type: Correction

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    The original article was published in Journal of Orthopaedic Surgery and Research 2021 16:18

  8. There is still lack of data on deep vein thrombosis (DVT) following bone trauma. This study aimed to determine the epidemiologic characteristics of deep venous thrombosis (DVT) of lower extremities following tibi...

    Authors: Yanbin Zhu, Wei Chen, Junyong Li, Kuo Zhao, Junzhe Zhang, Hongyu Meng, Yingze Zhang and Qi Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:113

    Content type: Research article

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  9. Treatment of early-onset scoliosis (EOS) is still a challenge to patients, families, and surgeons. Previous studies have indicated that EOS patients are at high risk for complications following growth-friendly...

    Authors: Mohammad Zarei, Mehdi Tavakoli, Ehsan Ghadimi, Alireza Moharrami, Ali Nili, Ali Vafaei, Seyed Saeed Tamehri Zadeh and Soroush Baghdadi

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:112

    Content type: Research article

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  10. We aimed to evaluate the safety and efficacy of intra-articular (IA) magnesium (Mg) for postoperative pain relief after arthroscopic knee surgery.

    Authors: Lijun Shi, Haiyun Zhu, Jinhui Ma, Li-Li Shi, Fuqiang Gao and Wei Sun

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:111

    Content type: Research article

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  11. Parallel osteotomy is essential for favorable osteotomy reduction and healing and technically challenging during diaphyseal ulnar shortening osteotomy (USO). This study aimed to evaluate the advantages of guid...

    Authors: Jong Woo Kang, Soo Min Cha, Sang-gyun Kim, In Cheul Choi, Dong Hun Suh and Jong Woong Park

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:110

    Content type: Research article

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  12. Osteonecrosis of the femoral head (ONFH) is a disabling disease, which often involves young patients. Recently, various hip-preserving surgeries were recommended to delay total hip arthroplasty (THA).

    Authors: Ke Jie, Wenjun Feng, Feilong Li, Keliang Wu, Jinlun Chen, Guanming Zhou, Huiliang Zeng and Yirong Zeng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:109

    Content type: Research article

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  13. This study aimed to prepare the polymethylmethacrylate (PMMA) bone cement release system with different concentrations of enoxaparin sodium (ES) and to investigate the release characteristics of ES after loadi...

    Authors: Hui Sun, Xinzhe Ma, Zhiyong Li, Jianning Liu, Wei Wang and Xiangbei Qi

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:108

    Content type: Research article

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  14. This study aimed to determine the effects of denosumab treatment on the joint destruction of Japanese females with rheumatoid arthritis (RA) and anti-cyclic citrullinated peptide (CCP) antibodies.

    Authors: Yu Mori, Takuya Izumiyama, Hiroaki Kurishima, Masayuki Kamimura, Kazuyoshi Baba, Naoko Mori and Eiji Itoi

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:107

    Content type: Research article

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  15. Elderly patients with intertrochanteric fractures exhibit post-traumatic hidden blood loss (HBL). This study aimed to evaluate the efficacy and safety of reducing post-traumatic HBL via early intravenous (IV) ...

    Authors: Huixu Ma, Hairuo Wang, Xiaotao Long, Zexiang Xu, Xiaohua Chen, Mingjin Li, Tao He, Wei Wang, Lei Liu and Xi Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:106

    Content type: Research article

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  16. Synovial fibroblasts (SFs) with the abnormal expressions of miRNAs are the key regulator in rheumatoid arthritis (RA). Low-expressed miR-140-3p was found in RA tissues. Therefore, we attempted to investigate t...

    Authors: Beibei Zu, Lin Liu, Jingya Wang, Meirong Li and Junxia Yang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:105

    Content type: Research article

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  17. Total hip arthroplasty (THA) for bony ankylosis is technically challenging in patients with ankylosing spondylitis (AS). This study aimed to determine the mid-term results of bilateral synchronous THA for bony...

    Authors: Lei Han, Renfu Quan, Zhenle Pei, Guoping Cao, Yungen Hu and Jingjing Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:104

    Content type: Research article

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  18. The coronavirus disease 2019 (COVID-19) pandemic is the largest global event in recent times, with millions of infected people and hundreds of thousands of deaths worldwide. Colombia has also been affected by ...

    Authors: Edwarth Soler, Sammy Nicolás Farah, Valeria P. Bustos, Sofía Elizabeth Muñoz Medina, Jairo Fernando Gómez, Ernesto Martinez Lema and Carlos Álvarez Moreno

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:103

    Content type: Research article

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  19. Although unloading of the joint is related to reduction of the local bone mineral density (BMD), little attention had been paid to the relationship between loading asymmetry and side-to-side difference of BMD ...

    Authors: Kohei Nishizawa, Kengo Harato, Yutaro Morishige, Shu Kobayashi, Yasuo Niki and Takeo Nagura

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:102

    Content type: Research article

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  20. Traditionally, the technique of modified tension band wires (MTBW) has been the most commonly used surgical procedure. The purpose of this study is to design a precise navigation device that can obtain a stand...

    Authors: Fuming Wang, Haolan Xiong, Xiaotao Long, Yang Li, Xiaohua Chen and Gang Wang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:101

    Content type: Research article

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  21. Hospital-acquired infections (HAIs) are an emerging global problem that increases in-hospital mortality, length of stay, and cost. We performed a 6-year retrospective study to provide valuable insight into app...

    Authors: Xiaowei Yang, Runsheng Guo, Banglin Xie, Qi Lai, Jiaxiang Xu, Niya Hu, Lijun Wan, Min Dai and Bin Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:100

    Content type: Research article

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  22. Although conservative treatment with circular plaster cast is the most commonly used method in distal radius fractures, the best method to apply it remains unclear.

    Authors: Alejandro Espejo-Reina, María T. Carrascal-Morillo and Alberto D. Delgado-Martínez

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:99

    Content type: Research article

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  23. To provide guidelines for surgery and reduce the incidence of fracture, this study analyzed the relationship between femoral fracture and related factors in direct anterior approach (DAA) total hip arthroplast...

    Authors: Guanjun Sun, Yi Yin, Yongjie Ye and Qingshan Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:98

    Content type: Research article

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  24. In orthopedic application, stress-shielding effects of implant materials cause bone loss, which often induces porosis, delayed bone healing, and other complications. We aimed to compare the stress-shielding ef...

    Authors: Xinwen Zhao, Wensen Jing, Zhe Yun, Xun Tong, Zhao Li, Jiajia Yu, Yaohui Zhang, Yabin Zhang, Zhixue Wang, Yanhua Wen, Heping Cai, Jun Wang, Baoan Ma and Haien Zhao

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:97

    Content type: Research article

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  25. The concept of minimally invasive surgery (MIS) was introduced in total knee arthroplasty (TKA) in the late 1990s. The number of MIS TKAs has clearly decreased in recent years. An implant designed specifically...

    Authors: Shinya Toyoda, Takao Kaneko, Yuta Mochizuki, Masaru Hada, Kazutaka Takada, Hiroyasu Ikegami and Yoshiro Musha

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:95

    Content type: Research article

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  26. Intramedullary nailing (IMN) is a conventional technique for the treatment of tibial shaft fractures. It has been suggested that the suprapatellar (SP) approach holds advantages over the traditional infrapatel...

    Authors: Nikhil Ponugoti, Branavan Rudran, Amr Selim, Sam Nahas and Henry Magill

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:94

    Content type: Systematic review

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  27. The rate of postoperative infection developing is higher after limb salvage surgery (LSS) following sarcoma resection compared with conventional arthroplasty. The goal of this study is to summarize our experie...

    Authors: Tiao Lin, Qinglin Jin, Xiaolin Mo, Zhiqiang Zhao, Xianbiao Xie, Changye Zou, Gang Huang, Junqiang Yin and Jingnan Shen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:93

    Content type: Research article

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  28. The central ridge of the patella is the thickest area of patella and varies among patients. This cadaveric study identified the location and thickness of the bone at the central patella ridge for bone-patellar...

    Authors: Thanathep Tanpowpong, Thun Itthipanichpong, Thanasil Huanmanop, Nonn Jaruthien and Nattapat Tangchitcharoen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:92

    Content type: Research article

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  29. Limited information exists on the incidence of postoperative deep venous thromboembolism (DVT) in patients with isolated patella fractures. The objective of this study was to investigate the postoperative inci...

    Authors: Zhanchao Tan, Hongzhi Hu, Xiangtian Deng, Jian Zhu, Yanbin Zhu, Dandan Ye, Xiaodong Cheng and Yingze Zhang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:90

    Content type: Research article

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  30. The transiliac-transsacral screw placement is a clinical challenge for surgeons. This study explored a point-to-point coaxial guide apparatus assisting the transiliac-transsacral screw insertion and aimed to i...

    Authors: Ze-hang Zheng, Fei Xu, Zheng-qiang Luo, Ye Ren, Tao Fu, Han-qing Xu and Bin-bin Liu

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:89

    Content type: Technical note

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  31. Regarding the repair of vertebral compression fractures, there is a lack of adequate biomechanical verification as to whether only half of the vertebral body and the upper and lower intervertebral discs affect...

    Authors: Ye Han, Xiaodong Wang, Jincheng Wu, Hanpeng Xu, Zepei Zhang, Kepeng Li, Yang Song and Jun Miao

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:88

    Content type: Research article

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  32. To evaluate the clinical efficacy of arthroscopic therapy with infrapatellar fat pad cell concentrates in treating knee cartilage lesions, we conducted a prospective randomized single-blind clinical study of c...

    Authors: Yiqin Zhou, Haobo Li, Dong Xiang, Jiahua Shao, Qiwei Fu, Yaguang Han, Jun Zhu, Yi Chen and Qirong Qian

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:87

    Content type: Research article

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  33. The aim of the present study was to explore the therapeutic effect and prognosis in patients with rib fractures and atelectasis after thoracic trauma in order to provide a basis for clinical decision-making in...

    Authors: Degang Yin, Jingang Lu, Jiansheng Wang, Biao Yan and Zhongshu Zheng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:86

    Content type: Research article

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  34. Previous studies showed overexpression of ABCG2 in a variety of tumor tissues, which could potentially indicate the probability of chemotherapy resistance. This study aimed to reveal the role of ABCG2 in the d...

    Authors: Hao Shu, Bin Yuan, Yao Huang, Lei Wang, Bing He, Qi Sun and Luning Sun

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:85

    Content type: Research article

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  35. Previous evidence suggested that perioperative anti-rheumatic therapy for patients receiving total knee arthroplasty (TKA) helped improve postoperative rehabilitation for rheumatoid arthritis (RA), yet long-te...

    Authors: Yi Ren, Qi Yang, Tim Luo, Jin Lin, Jin Jin, Wenwei Qian, Xisheng Weng and Bin Feng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:84

    Content type: Research article

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  36. Whether resurface the patella or not in total knee arthroplasty (TKA) was controversial. In 2013, we conducted a meta-analysis of randomized controlled trials (RTCs). After that, plenty of studies have been ca...

    Authors: Kai Chen, Xiaoyu Dai, Lidong Li, Zhigang Chen, Haidong Cui and Shujun Lv

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:83

    Content type: Systematic review

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  37. To compare the specificity and sensitivity of preoperative D-dimer and age-adjusted D-dimer value for predicting the incidence of the DVT preoperatively in total joint arthroplasty (TJA) patients.

    Authors: Jian Xiang Wu, Jiang Hui Qing, Yao Yao, Dong Yang Chen and Qing Jiang

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:82

    Content type: Research article

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  38. The aim of this study was to evaluate the efficacy of local infiltration anaesthesia (LIA) during primary total hip arthroplasty (THA) via a posterolateral approach under general anaesthesia and to compare the...

    Authors: Qiang Xiao, Bing Xu, Haoyang Wang, Zhenyu Luo, Mingcheng Yuan, Zongke Zhou and Fuxing Pei

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:81

    Content type: Research article

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  39. Only a few studies have described the effect of full arthroscopic surgery in treatment of excessive lateral pressure syndrome (ELPS). Therefore, the purpose of this study was to assess the clinical efficacy an...

    Authors: Cheng-Liang Wang, Ji-Bin Chen and Te Li

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:80

    Content type: Research article

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  40. Alumina-titanium (Al2O3-Ti) biocomposites have been recently developed with improved mechanical properties for use in heavily loaded orthopedic sites. Their biological performance, however, has not been investiga...

    Authors: Marjan Bahraminasab, Samaneh Arab, Manouchehr Safari, Athar Talebi, Fatemeh Kavakebian and Nesa Doostmohammadi

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:79

    Content type: Research article

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  41. Periprosthetic fractures of the distal femur above a total knee arthroplasty (TKA) have traditionally been managed by locking compression plating (LCP). This technique is technically demanding and is associate...

    Authors: Henry Magill, Nikhil Ponugoti, Amr Selim and James Platt

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:78

    Content type: Systematic review

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  42. As the ultimate method for the treatment of osteoarthritis, total knee arthroplasty (TKA) has been widely used in the clinic. Local injection of multimodal cocktails, including corticosteroids, is commonly use...

    Authors: Qi Li, Guo Mu, Xiangbo Liu and Milian Chen

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:77

    Content type: Research article

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    The Correction to this article has been published in Journal of Orthopaedic Surgery and Research 2021 16:200

  43. The risk factors of postoperative delirium (POD), a serious while preventable complication, developed by patients undergoing knee and replacement surgery are still under investigation. In this systematic revie...

    Authors: Xiao Rong, Zi-chuan Ding, Hao-da Yu, Shun-Yu Yao and Zong-Ke Zhou

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:76

    Content type: Systematic review

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  44. The rapid progressive cervical spondylotic myelopathy (rp-CSM) which had a course of CSM less than 1 month and suffered rapidly progressive neurological deterioration had few reports. Therefore, it is importan...

    Authors: Weiyang Zhong, Lin Wang, Tianji Huang and Xiaoji Luo

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:75

    Content type: Research article

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  45. Mandibular fracture healing is a complex process involving nerves and growth factors. Nerve growth factor (NGF) not only facilitates the maintenance of sympathetic neurite growth but also stimulates other grow...

    Authors: Sen Yang, Jiao Cheng, Cheng Man, Lian Jiang, Guogeng Long, Wenjun Zhao and Dexin Zheng

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:74

    Content type: Research article

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  46. Percutaneous vertebroplasty (PVP) is a routine operation for the treatment of osteoporotic lumbar compression fractures (OLCFs). As is well known, unilateral puncture is a common method. However, with the conv...

    Authors: Wenwu Zhang, Shenpeng Liu, Xianhua Liu, Xiang Li, Le Wang and Yong Wan

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:73

    Content type: Research article

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  47. Heat shock protein 22 (HSP22) belongs to class I of the small HSP family that displays ubiquitous expression in osteoblasts. We previously demonstrated that prostaglandin F2α (PGF2α), a potent bone remodeling ...

    Authors: Gen Kuroyanagi, Go Sakai, Takanobu Otsuka, Naohiro Yamamoto, Kazuhiko Fujita, Tetsu Kawabata, Rie Matsushima-Nishiwaki, Osamu Kozawa and Haruhiko Tokuda

    Citation: Journal of Orthopaedic Surgery and Research 2021 16:72

    Content type: Research article

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